Carbamic Acid

Carbamic Acid

SCHEMBL15212134

CCCCN(CCCC)CCCN.NC(=O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 4/20 0.44
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA9 Q16790 2/20 0.43
PHF8 Q9UPP1 2/20 0.42
KDM4C Q9H3R0 2/20 0.42
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
CHRM2 P08172 1/20 0.39
CYP3A4 P08684 1/20 0.39
HTR1A P08908 1/20 0.39
GAA P10253 1/20 0.39
CYP2D6 P10635 1/20 0.39
DRD3 P35462 1/20 0.39
SCN1A P35498 1/20 0.39
SLC6A3 Q01959 1/20 0.39
KCNH2 Q12809 1/20 0.39
SCN2A Q99250 1/20 0.39
SCN3A Q9NY46 1/20 0.39
DNM1 Q05193 7/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL28649191 0.91 KDM5A (0.50) KDM5ACA12CA1CA9PHF8
SCHEMBL181644 0.86 DNM1 (0.50) CA12CA1CA9CHRM2DNM1
SCHEMBL924962 0.86 DNM1 (0.50) CA12CA1CA9CHRM2DNM1
SCHEMBL11592670 0.86 DNM1 (0.50) CA12CA1CA9CHRM2DNM1
SCHEMBL13232029 0.84 DNM1 (0.48) KDM5APHF8CHRM2DNM1MEN1
SCHEMBL15188890 0.84 DNM1 (0.48) KDM5APHF8CHRM2DNM1MEN1
SCHEMBL14592914 0.84 DNM1 (0.48) CA12CA1CA9CHRM2DNM1
SCHEMBL16977064 0.83 KDM5A (0.59) KDM5APHF8KDM4CLMNACYP2D6
SCHEMBL17035584 0.81 DNM1 (0.52) KDM5APHF8KDM4CCHRM2DNM1
SCHEMBL17035583 0.81 DNM1 (0.52) KDM5APHF8KDM4CCHRM2DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015184326-A1 CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS CERULEAN PHARMA INC. (US) 2015-12-03 WO disclosed
WO-2015057847-A1 CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS CERULEAN PHARMA INC. (US) 2015-04-23 WO disclosed
EP-2817345-A1 CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS Cerulean Pharma Inc. (US) 2014-12-31 EP disclosed
US-20140037573-A1 CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS CERULEAN PHARMA INC (US) 2014-02-06 US disclosed
WO-2013126564-A1 CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS CERULEAN PHARMA INC. (US) 2013-08-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140037573-A1 CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS SYNCRIP, EXOSC5, EXOSC9 KDM5A 3869/4885CA12 657/4885CA1 1929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.