Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706703 | 0.89 | KIF11 (0.73) | KIF11KCNH2ALDH1A1CA4LTA4H | |
| SCHEMBL10877618 | 0.89 | KIF11 (0.73) | KIF11KCNH2ALDH1A1CA4LTA4H | |
| SCHEMBL15212073 | 0.88 | KIF11 (0.58) | KIF11KCNH2ALDH1A1LMNAHTT | |
| SCHEMBL28076878 | 0.86 | KIF11 (0.55) | KIF11KCNH2ALDH1A1LMNAHTT | |
| SCHEMBL28076876 | 0.86 | KIF11 (0.55) | KIF11KCNH2ALDH1A1LMNAHTT | |
| SCHEMBL462675 | 0.85 | KIF11 (0.62) | KIF11KCNH2CA4LTA4HLMNA | |
| SCHEMBL13060384 | 0.85 | KIF11 (0.62) | KIF11KCNH2CA4LTA4HLMNA | |
| SCHEMBL950778 | 0.84 | KIF11 (0.54) | KIF11KCNH2SMN1; SMN2 | |
| SCHEMBL5058831 | 0.84 | KIF11 (0.66) | KIF11KCNH2CA4LTA4HLMNA | |
| SCHEMBL28515838 | 0.84 | KIF11 (0.66) | KIF11KCNH2CA4LTA4HLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013126034-A1 | SYNTHESIS OF HIGH PURITY DMT-C3-DISULFIDE PHOSPHORAMIDITE | CHEMGENES CORPORATION (US) | 2013-08-29 | — | — | WO | disclosed |