Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10877618 | 1.00 | KIF11 (0.73) | KIF11KCNH2MEN1KMT2ACA4 | |
| SCHEMBL15212173 | 0.89 | KIF11 (0.68) | KIF11KCNH2MEN1KMT2ACA4 | |
| SCHEMBL1974299 | 0.85 | KIF11 (0.61) | KIF11KCNH2 | |
| SCHEMBL15212059 | 0.85 | KIF11 (0.71) | KIF11KCNH2CA4LTA4HLMNA | |
| SCHEMBL22150730 | 0.85 | KIF11 (0.71) | KIF11KCNH2CA4LMNAHTT | |
| SCHEMBL7708779 | 0.83 | KIF11 (0.69) | KIF11KCNH2CA4LMNAHTT | |
| Fluoride SCHEMBL27680958 | 0.83 | KIF11 (0.59) | KIF11KCNH2 | |
| SCHEMBL19822096 | 0.82 | KIF11 (0.56) | KIF11KCNH2MEN1KMT2AALDH1A1 | |
| SCHEMBL8972758 | 0.82 | KIF11 (0.68) | KIF11KCNH2LTA4HLMNAHTT | |
| SCHEMBL29060869 | 0.82 | KIF11 (0.88) | KIF11KCNH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208234-A1 | POLY(ETHER-THIOETHER), POLY(ETHER-SULFOXIDE) AND POLY(ETHER-SULFONE) NUCLEIC ACIDS | BIO-RAD LABORATORIES, INC. (US) | 2002-05-29 | — | — | EP | disclosed |
| US-6348583-B1 | NUCLEOBASE CONTAINING POLYTHIOETHERS SYNTHESIZED ON POLYETHYLENE GLYCOL, SUCCINIC ANHYDRIDE AND PROPYLAMINE MODIFIED GLASS; NUCLEIC ACID MIMETICS | BIO-RAD LABORATORIES, INC. | 2002-02-19 | — | — | US | disclosed |
| WO-2001016365-A1 | POLY(ETHER-THIOETHER), POLY(ETHER-SULFOXIDE) AND POLY(ETHER-SULFONE) NUCLEIC ACIDS | BIO-RAD LABORATORIES, INC. (US) | 2001-03-08 | — | — | WO | disclosed |