Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28108200 | 0.78 | ACP3 (0.46) | HSD17B10HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5012463 | 0.78 | ACP3 (0.46) | HSD17B10HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29599325 | 0.78 | KDM4E (0.53) | HSD17B10HPGDCYP1A2KIF11ALDH1A1 | |
| SCHEMBL1161290 | 0.78 | KDM4E (0.53) | HSD17B10HPGDCYP1A2KIF11ALDH1A1 | |
| SCHEMBL2187746 | 0.77 | HSD17B10 (0.43) | HSD17B10HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7028514 | 0.77 | KIF11 (0.45) | HSD17B10HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7613484 | 0.76 | ALDH1A1 (0.43) | HSD17B10HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3003485 | 0.75 | CYP3A4 (0.42) | HSD17B10HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6241697 | 0.75 | CYP1A2 (0.42) | HSD17B10HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6242753 | 0.75 | CYP1A2 (0.42) | HSD17B10HPGDCYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013126034-A1 | SYNTHESIS OF HIGH PURITY DMT-C3-DISULFIDE PHOSPHORAMIDITE | CHEMGENES CORPORATION (US) | 2013-08-29 | — | — | WO | claimed |