Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.94 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | TSHR | P16473 | 4/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.77 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | THRB | P10828 | 1/20 | 0.77 |
| ▸ | RECQL | P46063 | 1/20 | 0.77 |
| ▸ | ATM | Q13315 | 1/20 | 0.77 |
| ▸ | KCNH3 | Q9ULD8 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66892 | 0.97 | TDP1 (1.00) | TDP1HSD17B10ALDH1A1TSHRALOX15 | |
| SCHEMBL28043814 | 0.94 | TDP1 (0.94) | TDP1HSD17B10ALDH1A1TSHRALOX15 | |
| SCHEMBL28043559 | 0.94 | TDP1 (0.94) | TDP1HSD17B10ALDH1A1TSHRALOX15 | |
| SCHEMBL23319717 | 0.94 | TDP1 (0.94) | TDP1HSD17B10ALDH1A1TSHRALOX15 | |
| Hydrochloric Acid SCHEMBL7407338 | 0.94 | TDP1 (0.94) | TDP1HSD17B10ALDH1A1TSHRALOX15 | |
| SCHEMBL21448661 | 0.90 | TDP1 (0.85) | TDP1HSD17B10ALDH1A1TSHRALOX15 | |
| SCHEMBL38820 | 0.87 | ALDH1A1 (1.00) | TDP1HSD17B10ALDH1A1TSHRALOX15 | |
| SCHEMBL8467092 | 0.85 | ALDH1A1 (0.95) | TDP1HSD17B10ALDH1A1TSHRALOX15 | |
| N,N'-Diphenyl-P-Phenylenediamine SCHEMBL10454790 | 0.85 | ALDH1A1 (0.95) | TDP1HSD17B10ALDH1A1TSHRALOX15 | |
| N,N'-Diphenyl-P-Phenylenediamine SCHEMBL10454791 | 0.85 | ALDH1A1 (0.95) | TDP1HSD17B10ALDH1A1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2817289-A2 | ASYMMETRIC SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOSULFONE COMPOUNDS | Celgene Corporation (US) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013126495-A2 | ASYMMETRIC SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOSULFONE COMPOUNDS | CELGENE CORPORATION (US) | 2013-08-29 | — | — | WO | disclosed |