SCHEMBL66892

SCHEMBL66892

CC(C)Nc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 1.00
HSD17B10 Q99714 5/20 0.81
ALDH1A1 P00352 5/20 0.81
TSHR P16473 4/20 0.81
ALOX15 P16050 3/20 0.81
ALOX12 P18054 3/20 0.81
CYP3A4 P08684 2/20 0.81
L3MBTL1 Q9Y468 2/20 0.81
LMNA P02545 1/20 0.81
THRB P10828 1/20 0.81
RECQL P46063 1/20 0.81
ATM Q13315 1/20 0.81
KCNH3 Q9ULD8 4/20 0.56
GAA P10253 1/20 0.50
MAPK1 P28482 2/20 0.48
HIF1A Q16665 1/20 0.48
KDM4E B2RXH2 1/20 0.45
CTSD P07339 1/20 0.45
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23319717 0.97 TDP1 (0.94) TDP1HSD17B10ALDH1A1TSHRALOX15
SCHEMBL28043814 0.97 TDP1 (0.94) TDP1HSD17B10ALDH1A1TSHRALOX15
SCHEMBL28043559 0.97 TDP1 (0.94) TDP1HSD17B10ALDH1A1TSHRALOX15
SCHEMBL15212378 0.97 TDP1 (0.94) TDP1HSD17B10ALDH1A1TSHRALOX15
Hydrochloric Acid SCHEMBL7407338 0.97 TDP1 (0.94) TDP1HSD17B10ALDH1A1TSHRALOX15
SCHEMBL21448661 0.92 TDP1 (0.85) TDP1HSD17B10ALDH1A1TSHRALOX15
SCHEMBL38820 0.90 ALDH1A1 (1.00) TDP1HSD17B10ALDH1A1TSHRALOX15
N,N'-Diphenyl-P-Phenylenediamine SCHEMBL10454790 0.88 ALDH1A1 (0.95) TDP1HSD17B10ALDH1A1TSHRALOX15
SCHEMBL8467092 0.88 ALDH1A1 (0.95) TDP1HSD17B10ALDH1A1TSHRALOX15
N,N'-Diphenyl-P-Phenylenediamine SCHEMBL10454791 0.88 ALDH1A1 (0.95) TDP1HSD17B10ALDH1A1TSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2576 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4685176-A1 2-COMPONENT FOAMS BASED ON ACETYLACETONATE AND AMINES Henkel AG & Co. KGaA (DE) 2026-01-28 EP claimed
EP-3949991-B1 ACELLULAR ROOT CANAL FILLER AND ACELLULAR DENTAL TISSUE REGENERATION PROMOTING KIT KOWA CO (JP) 2025-07-23 EP claimed
CN-116622081-B Non-noble metal cage MOFs catalyst for producing N-benzamide and preparation method and application thereof 内蒙古大学 2025-06-24 CN claimed
WO-2025107117-A1 COSMETIC COMPOSITION WITH A C-GLYCOSIDE, NIACINAMIDE AND PANTHENOL L'OREAL (FR) 2025-05-30 WO claimed
US-20250109337-A1 ALKALINE SUSPENDING SYSTEMS CONSTRUCTED FROM HYDROTROPES AND AMINES STEPAN CO (US) 2025-04-03 US claimed
CN-119630281-A Alkaline suspension system built up from hydrotrope and amine 斯蒂潘公司 2025-03-14 CN claimed
CN-118978506-A Preparation method of epigallocatechin gallate alkyl derivative 湖南成大生物科技有限公司 2024-11-19 CN claimed
CN-118702664-A Method for preparing (-) EGCG by photocatalysis debenzylation reaction 湖南成大生物科技有限公司 2024-09-27 CN claimed
CN-115322132-B N-substituted indole compound and synthesis method thereof 陕西科技大学 2024-05-28 CN claimed
CN-117801214-A High-strength wear-resistant thermoplastic polyurethane elastomer and preparation method and application thereof 万华化学集团股份有限公司 2024-04-02 CN claimed
US-4978332-A Reduced effect on cells distant from the site MATRIX PHARMACEUTICAL, INC. (US) 1990-12-18 US claimed
EP-0335966-A4 VASOCONSTRICTIVE SUBSTANCES IN COMBINATION WITH CYTOTOXIC AGENTS. MATRIX PHARMA INC (US) 1990-02-20 EP claimed
EP-0335966-A1 VASOCONSTRICTIVE SUBSTANCES IN COMBINATION WITH CYTOTOXIC AGENTS MATRIX PHARMACEUTICALS, INC. (US) 1989-10-11 EP claimed
WO-1989002734-A1 VASOCONSTRICTIVE SUBSTANCES IN COMBINATION WITH CYTOTOXIC AGENTS MATRIX PHARMACEUTICALS, INC. (US) 1989-04-06 WO claimed
EP-0286029-A1 Alkylation of aromatic amines over A1 exchanged zeolites AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-10-12 EP claimed
US-4410730-A Process for the production of o-(N-monosubstituted amino)benzyl alcohols SHIONOGI & CO., LTD. (JP) 1983-10-18 US claimed
EP-0010270-B1 ALPHA-AZOLYL-ALPHA-PHENYLACETIC ACID DERIVATIVES, THEIR PRODUCTION, FUNGICIDES CONTAINING THEM, METHOD FOR COMBATING FUNGI AND FOR THE PRODUCTION OF FUNGICIDES BASF Aktiengesellschaft (DE) 1981-11-04 EP claimed
US-4062893-A SULFURIC ACID CATALYST NEW JAPAN CHEMICAL COMPANY, LIMITED (JA) 1977-12-13 US claimed
US-4000197-A FROM PHENYLACETONES AND METHYL BENZYLAMINE, REDUCTION, HYDROGENOLYSIS THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1976-12-28 US claimed
US-3933717-A Water soluble linear macroamine polymers and method of producing them B. R. CHEMICAL CO., LTD. (JA) 1976-01-20 US claimed