Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 8/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15212692 | 0.87 | ESR1 (0.35) | FFAR1ESR1ESR2MEN1KMT2A | |
| SCHEMBL15212693 | 0.79 | FFAR1 (0.45) | FFAR1ESR1MEN1KMT2ATBXAS1 | |
| SCHEMBL15211694 | 0.77 | IKBKB (0.36) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL15211500 | 0.75 | ESR1 (0.39) | FFAR1ESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL15211431 | 0.75 | TP53 (0.35) | ESR1ESR2MEN1KMT2AALDH1A1 | |
| SCHEMBL15211853 | 0.74 | MBOAT4 (0.43) | FFAR1ESR1ESR2 | |
| SCHEMBL15211424 | 0.73 | ESR1 (0.45) | ESR1ESR2KDM4ECNR2HTT | |
| SCHEMBL15211206 | 0.73 | PPARD (0.39) | FFAR1ESR1ESR2 | |
| SCHEMBL15212674 | 0.71 | FFAR1 (0.48) | FFAR1MEN1KMT2ATBXAS1ALDH1A1 | |
| SCHEMBL15212691 | 0.71 | PPARD (0.54) | FFAR1MEN1KMT2AALOX5APALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |