Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15212672 | 0.87 | FFAR1 (0.45) | ESR1ESR2FFAR1MEN1LMNA | |
| SCHEMBL15212601 | 0.80 | PPARD (0.40) | MAPTPPARDPPARAL3MBTL1FFAR1 | |
| SCHEMBL15211853 | 0.80 | MBOAT4 (0.43) | ESR1ESR2PPARDPPARAFFAR1 | |
| SCHEMBL15211206 | 0.76 | PPARD (0.39) | ESR1ESR2PPARDPPARAFFAR1 | |
| SCHEMBL15211763 | 0.75 | PPARD (0.40) | ESR1PPARDPPARAFFAR1PPARG | |
| SCHEMBL15212600 | 0.74 | PPARD (0.35) | PPARDPPARAKMT2AALDH1A1HDAC3 | |
| SCHEMBL15211378 | 0.73 | CA2 (0.40) | ESR1ESR2 | |
| SCHEMBL15212615 | 0.73 | PPARD (0.61) | PPARDPPARAFFAR1PPARG | |
| SCHEMBL17431311 | 0.73 | PPARA (0.40) | MAPTPPARDPPARAL3MBTL1FFAR1 | |
| SCHEMBL15212694 | 0.73 | PPARD (0.48) | MAPTPPARDPPARAL3MBTL1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |