Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | HAT1 | O14929 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17431434 | 0.92 | PPARD (0.42) | KITHPGDSMN1; SMN2POLBS1PR1 | |
| SCHEMBL17444908 | 0.87 | HDAC8 (0.42) | HPGDSMN1; SMN2POLBLMNAHDAC8 | |
| SCHEMBL17431412 | 0.83 | HAT1 (0.37) | KITHPGDSMN1; SMN2POLBLMNA | |
| SCHEMBL15220402 | 0.82 | HDAC8 (0.47) | HPGDSMN1; SMN2POLBLMNAHDAC8 | |
| SCHEMBL17444909 | 0.81 | HTT (0.42) | HPGDSMN1; SMN2POLBLMNAHDAC8 | |
| SCHEMBL17444907 | 0.81 | HDAC8 (0.44) | HPGDSMN1; SMN2POLBLMNAHDAC8 | |
| SCHEMBL15220395 | 0.80 | HDAC8 (0.46) | HPGDSMN1; SMN2POLBLMNAHDAC8 | |
| SCHEMBL15211267 | 0.78 | PTGDR (0.43) | HPGDSMN1; SMN2POLBLMNAHDAC8 | |
| SCHEMBL15212687 | 0.77 | SLC26A4 (0.41) | KITHPGDSMN1; SMN2POLBLMNA | |
| SCHEMBL15211600 | 0.77 | PPARD (0.48) | SMN1; SMN2POLBHDAC8ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238639-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-01-19 | — | — | US | disclosed |
| US-9238639-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-01-19 | — | — | US | disclosed |
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |