Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A4 | O43511 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.37 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HAT1 | O14929 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15211337 | 0.80 | POLB (0.48) | SLC26A4POLBSMN1; SMN2PTGER1FABP3 | |
| SCHEMBL15211265 | 0.78 | SLC26A4 (0.46) | SLC26A4POLBSMN1; SMN2PTGER1FABP3 | |
| SCHEMBL17431434 | 0.78 | PPARD (0.42) | SLC26A4POLBSMN1; SMN2HPGDPTGER1 | |
| SCHEMBL15212688 | 0.77 | KIT (0.39) | POLBSMN1; SMN2HPGDPTGER1KIT | |
| SCHEMBL17431412 | 0.76 | HAT1 (0.37) | SLC26A4POLBSMN1; SMN2HPGDPTGER1 | |
| SCHEMBL15211549 | 0.75 | SLC26A4 (0.61) | SLC26A4POLBHPGD | |
| SCHEMBL15211565 | 0.71 | HDAC8 (0.46) | SLC26A4POLBSMN1; SMN2HPGDPTGER1 | |
| SCHEMBL15211602 | 0.71 | HDAC8 (0.40) | SLC26A4POLBSMN1; SMN2PTGER1FABP3 | |
| SCHEMBL15211374 | 0.68 | POLB (0.45) | SLC26A4POLBSMN1; SMN2PTGER1FABP3 | |
| SCHEMBL15212722 | 0.68 | HTT (0.43) | SLC26A4POLBSMN1; SMN2PTGER1FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |