Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 9/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 7/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14888176 | 0.87 | ACVRL1 (0.46) | ACVRL1KDM4EALDH1A1LMNA | |
| SCHEMBL5137764 | 0.74 | ACVRL1 (0.46) | ACVRL1 | |
| SCHEMBL57703 | 0.72 | FGFR1 (0.48) | ACVRL1 | |
| SCHEMBL5077251 | 0.70 | ACVRL1 (0.38) | ACVRL1KDM4EALDH1A1 | |
| SCHEMBL15019846 | 0.68 | FGFR1 (0.42) | ACVRL1 | |
| SCHEMBL15020405 | 0.68 | FGFR1 (0.38) | ACVRL1LMNA | |
| SCHEMBL16011267 | 0.68 | ACVRL1 (0.62) | ACVRL1KDM4EALDH1A1 | |
| SCHEMBL59608 | 0.67 | ACVRL1 (0.64) | ACVRL1KDM4E | |
| SCHEMBL15019887 | 0.65 | FGFR1 (0.39) | ACVRL1 | |
| SCHEMBL15019263 | 0.65 | FGFR1 (0.36) | ACVRL1ALDH1A1LMNAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2817311-A1 | SUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND USES THEREOF | Bayer Intellectual Property GmbH (DE) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013124316-A1 | SUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND USES THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-29 | — | — | WO | disclosed |