Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24829914 | 0.82 | TSHR (0.45) | TSHRNPSR1 | |
| SCHEMBL1387914 | 0.72 | — | — | |
| SCHEMBL908642 | 0.72 | — | — | |
| SCHEMBL16423425 | 0.67 | CYP19A1 (0.36) | TSHRNPSR1 | |
| SCHEMBL16844627 | 0.66 | — | — | |
| SCHEMBL11179820 | 0.65 | ALPL (0.34) | TSHR | |
| SCHEMBL18698735 | 0.64 | DPP4 (0.33) | TSHRNPSR1 | |
| SCHEMBL15193085 | 0.64 | ALDH1A1 (0.33) | TSHR | |
| SCHEMBL2755818 | 0.64 | MAPT (0.41) | TSHRNPSR1GAAHTT | |
| SCHEMBL8064230 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013123222-A1 | PROCESS FOR PREPARING 4-AMINO-5-BIPHENYL-4-YL-2-HYDROXYMETHYL-2-METHYL-PENTANOIC ACID COMPOUNDS | THERAVANCE, INC. (US) | 2013-08-22 | — | — | WO | disclosed |