Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15214004 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMIMPDH2TPMTTDP1 | |
| SCHEMBL15214262 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2PKMIMPDH2TPMTTDP1 | |
| SCHEMBL27974983 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2PKMIMPDH2TPMTTDP1 | |
| SCHEMBL27640077 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMIMPDH2TPMTTDP1 | |
| SCHEMBL27565467 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMIMPDH2TPMTTDP1 | |
| SCHEMBL27287426 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMIMPDH2TPMTTDP1 | |
| SCHEMBL1202914 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMIMPDH2TPMTTDP1 | |
| SCHEMBL15214235 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2PKMIMPDH2TPMTTDP1 | |
| SCHEMBL5589481 | 0.77 | IMPDH2 (0.48) | SMN1; SMN2PKMIMPDH2TPMTTDP1 | |
| SCHEMBL7007613 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2PKMIMPDH2TPMTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8519176-B1 | Process for preparation of substituted P-aminophenol | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-08-27 | — | — | US | disclosed |