Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 15/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
| ▸ | GLS2 | Q9UI32 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | MPEG1 | Q2M385 | 7/20 | 0.44 |
| ▸ | XIAP | P98170 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053777 | 1.00 | PTPN1 (0.54) | PTPN1ACHEBACE1ALOX5PTGS2 | |
| SCHEMBL13174443 | 0.91 | PTPN1 (0.47) | PTPN1ACHEBACE1ALOX5PTGS2 | |
| Bromide SCHEMBL22265994 | 0.89 | PTPN1 (0.46) | PTPN1ACHEBACE1ALOX5PTGS2 | |
| SCHEMBL18840113 | 0.87 | PTPN1 (0.43) | PTPN1ACHEBACE1ALOX5PTGS2 | |
| SCHEMBL5080244 | 0.84 | STAT3 (0.47) | PTPN1ACHEBACE1ALOX5PTGS2 | |
| SCHEMBL13174362 | 0.84 | STAT3 (0.47) | PTPN1ACHEBACE1ALOX5PTGS2 | |
| SCHEMBL18104368 | 0.84 | STAT3 (0.47) | PTPN1ACHEBACE1ALOX5PTGS2 | |
| SCHEMBL10580225 | 0.80 | ACHE (0.70) | PTPN1ACHEBACE1ALOX5PTGS2 | |
| SCHEMBL13174567 | 0.80 | ACHE (0.70) | PTPN1ACHEBACE1ALOX5PTGS2 | |
| SCHEMBL9588146 | 0.80 | ACHE (0.70) | PTPN1ACHEBACE1ALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518915-B2 | Use of mitochondrially-addressed compounds for preventing and treating cardiovascular diseases | MITOTECH SA (LU) | 2013-08-27 | — | — | US | disclosed |
| US-8518915-B2 | Use of mitochondrially-addressed compounds for preventing and treating cardiovascular diseases | MITOTECH SA (LU) | 2013-08-27 | — | — | US | disclosed |