SCHEMBL7053777

SCHEMBL7053777

CCCCCCCCCCC1=CC(=O)C(C)=C(C)C1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.54
ACHE P22303 1/20 0.53
BACE1 P56817 1/20 0.53
ALOX5 P09917 15/20 0.50
PTGS2 P35354 4/20 0.50
GLS2 Q9UI32 1/20 0.50
STAT3 P40763 1/20 0.48
MPEG1 Q2M385 7/20 0.44
XIAP P98170 2/20 0.44
GPR84 Q9NQS5 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPT P10636 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
PTGES O14684 1/20 0.44
USP2 O75604 1/20 0.44
TP53 P04637 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15214280 1.00 PTPN1 (0.54) PTPN1ACHEBACE1ALOX5PTGS2
SCHEMBL13174443 0.91 PTPN1 (0.47) PTPN1ACHEBACE1ALOX5PTGS2
Bromide SCHEMBL22265994 0.89 PTPN1 (0.46) PTPN1ACHEBACE1ALOX5PTGS2
SCHEMBL18840113 0.87 PTPN1 (0.43) PTPN1ACHEBACE1ALOX5PTGS2
SCHEMBL5080244 0.84 STAT3 (0.47) PTPN1ACHEBACE1ALOX5PTGS2
SCHEMBL13174362 0.84 STAT3 (0.47) PTPN1ACHEBACE1ALOX5PTGS2
SCHEMBL18104368 0.84 STAT3 (0.47) PTPN1ACHEBACE1ALOX5PTGS2
SCHEMBL10580225 0.80 ACHE (0.70) PTPN1ACHEBACE1ALOX5PTGS2
SCHEMBL13174567 0.80 ACHE (0.70) PTPN1ACHEBACE1ALOX5PTGS2
SCHEMBL9588146 0.80 ACHE (0.70) PTPN1ACHEBACE1ALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328130-B2 Method of treating organism by biologically active compounds specifically delivered into mitochondria, pharmaceutical composition required for the use of the method and a compound applicable for this purpose MITOTECH S.A. (LU) 2016-05-03 US disclosed
US-9328130-B2 Method of treating organism by biologically active compounds specifically delivered into mitochondria, pharmaceutical composition required for the use of the method and a compound applicable for this purpose MITOTECH S.A. (LU) 2016-05-03 US disclosed
WO-2003075820-A1 METHODS AND DEVICES FOR TRANSDERMAL DELIVERY OF ANTI-AGING COMPOUNDS FOR TREATMENT AND PREVENTION OF FACIAL OR NECK SKIN AGING JASON ENTERPRISES, INC. (US) 2003-09-18 WO disclosed
US-20030167556-A1 Methods and devices for transdermal delivery of anti-aging compounds for treatment and prevention of facial or neck skin aging CONSUMERS CHOICE SYSTEMS, INC. 2003-09-11 US disclosed
EP-0859592-B1 SKIN-CARE AGENT FOR AGEING SKIN BEIERSDORF AG (DE) 2003-05-28 EP disclosed
US-6503523-B2 In topical preparations for acne, skin aging, or skin whitening GS DEVELOPMENT A.B. (SE) 2003-01-07 US disclosed
US-20020182199-A1 Skin Care agents containing combinations of active agents consisting of vitamin a derivatives and ubi-or plastoquinones GS DEVELOPMENT A.B. 2002-12-05 US disclosed
US-6428779-B1 TOPICAL COSMETICS CONTAINING STEROLS, UBIQUINONES AND ANALGESIC PLANT EXTRACTS; OXIDATION RESISTANCE; SIDE EFFECT REDUCTION BEIERSDORF AG (DE) 2002-08-06 US disclosed
EP-1073412-B1 SKIN CARE AGENTS CONTAINING COMBINATIONS OF ACTIVE AGENTS CONSISTING OF VITAMIN A DERIVATIVES AND UBI- OR PLASTOQUINONES GS DEV AB (SE) 2001-11-28 EP disclosed
EP-0751763-B1 SUBSTANCES, COMBINATIONS OF ACTIVE SUBSTANCES AND COMPOSITIONS AGAINST SKIN AGEING BEIERSDORF AG (DE) 2001-10-24 EP disclosed
EP-1073412-A1 SKIN CARE AGENTS CONTAINING COMBINATIONS OF ACTIVE AGENTS CONSISTING OF VITAMIN A DERIVATIVES AND UBI- OR PLASTOQUINONES GS DEVELOPMENT AB (SE) 2001-02-07 EP disclosed
EP-0751762-B1 SKIN CARE PRODUCT BEIERSDORF AG (DE) 2000-12-06 EP disclosed
WO-1999056719-A1 SKIN CARE AGENTS CONTAINING COMBINATIONS OF ACTIVE AGENTS CONSISTING OF VITAMIN A DERIVATIVES AND UBI- OR PLASTOQUINONES GS DEVELOPMENT A.B. (SE) 1999-11-11 WO disclosed
US-5889062-A UBIQUINONES BEIERSDORF AG (DE) 1999-03-30 US disclosed
EP-0859592-A1 SKIN-CARE AGENT FOR AGEING SKIN Beiersdorf Aktiengesellschaft (DE) 1998-08-26 EP disclosed
WO-1997012591-A1 SKIN-CARE AGENT FOR AGEING SKIN BEIERSDORF AG (DE) 1997-04-10 WO disclosed
EP-0751763-A1 SUBSTANCES, COMBINATIONS OF ACTIVE SUBSTANCES AND COMPOSITIONS AGAINST SKIN AGEING Beiersdorf Aktiengesellschaft (DE) 1997-01-08 EP disclosed
EP-0751762-A1 SKIN CARE PRODUCT Beiersdorf Aktiengesellschaft (DE) 1997-01-08 EP disclosed
WO-1995026181-A1 SUBSTANCES, COMBINATIONS OF ACTIVE SUBSTANCES AND COMPOSITIONS AGAINST SKIN AGEING BEIERSDORF AG (DE) 1995-10-05 WO disclosed
WO-1995026180-A1 SKIN CARE PRODUCT BEIERSDORF AG (DE) 1995-10-05 WO disclosed