Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154444 | 0.86 | PRKCZ (0.59) | PRKCZMAPTHSD17B10HTTALOX15 | |
| SCHEMBL15626743 | 0.84 | PRKCZ (0.46) | PRKCZMAPTHSD17B10HTTALOX15 | |
| SCHEMBL2476223 | 0.83 | PRKCZ (0.56) | PRKCZMAPTHSD17B10HTTALOX15 | |
| SCHEMBL27870852 | 0.83 | PRKCZ (0.56) | PRKCZMAPTHSD17B10HTTALOX15 | |
| SCHEMBL4259769 | 0.83 | PRKCZ (0.56) | PRKCZMAPTHSD17B10HTTALOX15 | |
| SCHEMBL9422075 | 0.82 | PRKCZ (0.55) | PRKCZMAPTHSD17B10HTTALOX15 | |
| SCHEMBL15629679 | 0.82 | KDR (0.52) | PRKCZMAPTHSD17B10HTTALDH1A1 | |
| SCHEMBL15629589 | 0.82 | PRKCZ (0.68) | PRKCZMAPTHSD17B10HTTALOX15 | |
| SCHEMBL12960178 | 0.82 | PRKCZ (0.63) | PRKCZMAPTHSD17B10HTTALOX15 | |
| SCHEMBL15629747 | 0.82 | PRKCZ (0.56) | PRKCZMAPTHSD17B10HTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9067928-B2 | Compounds and methods of use | ABBVIE INC. (US) | 2015-06-30 | — | — | US | disclosed |
| US-20140084578-A1 | AZO COMPOUND, AQUEOUS SOLUTION, INK COMPOSITION, INK FOR INKJET RECORDING, INKJET RECORDING METHOD, INK CARTRIDGE FOR INKJET RECORDING, AND INKJET RECORDED MATERIAL | FUJIFILM CORPORATION (JP) | 2014-03-27 | — | — | US | disclosed |
| US-8518970-B2 | Compounds and methods of use | ABBVIE INC. (US) | 2013-08-27 | — | — | US | disclosed |