SCHEMBL4259769

SCHEMBL4259769

N#Cc1c(-c2ccc(Cl)cc2)csc1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCZ Q05513 2/20 0.56
MAPT P10636 5/20 0.55
HSD17B10 Q99714 3/20 0.55
ALOX15 P16050 2/20 0.55
HTT P42858 2/20 0.55
KDM4E B2RXH2 5/20 0.48
ALDH1A1 P00352 3/20 0.48
HPGD P15428 3/20 0.48
NPSR1 Q6W5P4 3/20 0.48
RXFP1 Q9HBX9 2/20 0.48
PPARG P37231 1/20 0.48
STAT3 P40763 1/20 0.48
NR2E3 Q9Y5X4 1/20 0.48
NCOR2 Q9Y618 1/20 0.48
ADORA2A P29274 3/20 0.46
ADORA1 P30542 3/20 0.46
ALOX5 P09917 1/20 0.44
PTGS2 P35354 1/20 0.44
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10154444 0.86 PRKCZ (0.59) PRKCZMAPTHSD17B10ALOX15HTT
SCHEMBL15214875 0.83 PRKCZ (0.60) PRKCZMAPTHSD17B10ALOX15HTT
SCHEMBL2476223 0.83 PRKCZ (0.56) PRKCZMAPTHSD17B10ALOX15HTT
SCHEMBL27870852 0.83 PRKCZ (0.56) PRKCZMAPTHSD17B10ALOX15HTT
SCHEMBL9422075 0.82 PRKCZ (0.55) PRKCZMAPTHSD17B10ALOX15HTT
SCHEMBL4488141 0.81 PRKCZ (0.55) PRKCZMAPTHSD17B10ALOX15HTT
SCHEMBL10654581 0.79 KDM4E (0.51) PRKCZMAPTKDM4EALDH1A1HPGD
SCHEMBL15629589 0.79 PRKCZ (0.68) PRKCZMAPTHSD17B10ALOX15HTT
SCHEMBL15629747 0.79 PRKCZ (0.56) PRKCZMAPTHSD17B10ALOX15HTT
SCHEMBL4469939 0.76 PRKCZ (0.50) PRKCZMAPTHSD17B10ALOX15HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140084578-A1 AZO COMPOUND, AQUEOUS SOLUTION, INK COMPOSITION, INK FOR INKJET RECORDING, INKJET RECORDING METHOD, INK CARTRIDGE FOR INKJET RECORDING, AND INKJET RECORDED MATERIAL FUJIFILM CORPORATION (JP) 2014-03-27 US disclosed
US-20140084578-A1 AZO COMPOUND, AQUEOUS SOLUTION, INK COMPOSITION, INK FOR INKJET RECORDING, INKJET RECORDING METHOD, INK CARTRIDGE FOR INKJET RECORDING, AND INKJET RECORDED MATERIAL FUJIFILM CORPORATION (JP) 2014-03-27 US disclosed
WO-2009101428-A1 POLYAZO COMPOUNDS AND THEIR USE IN INK JET PRINTING FUJIFILM IMAGING COLORANTS LIMITED (GB) 2009-08-20 WO disclosed