Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14212668 | 0.88 | ALDH1A1 (0.47) | ALDH1A1TSHRCA12CA2CA3 | |
| SCHEMBL14263632 | 0.88 | CA12 (0.47) | ALDH1A1TSHRCA12CA2CA3 | |
| SCHEMBL13100412 | 0.82 | CA12 (0.47) | ALDH1A1TSHRCA12CA2CA3 | |
| SCHEMBL476533 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRCA12CA2CA3 | |
| SCHEMBL15620 | 0.78 | ALDH1A1 (0.60) | ALDH1A1TSHRCA12CA2CA3 | |
| SCHEMBL15444951 | 0.78 | CA12 (0.57) | ALDH1A1TSHRCA12CA2CA3 | |
| SCHEMBL82581 | 0.78 | CA12 (0.57) | ALDH1A1TSHRCA12CA2CA3 | |
| SCHEMBL12794518 | 0.78 | CA12 (0.57) | ALDH1A1TSHRCA12CA2CA3 | |
| SCHEMBL23923650 | 0.76 | ALDH1A1 (0.67) | ALDH1A1TSHRCA12CA2CA3 | |
| SCHEMBL23939990 | 0.76 | ALDH1A1 (0.67) | ALDH1A1TSHRCA12CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8519189-B2 | Polymers for reversing heparin-based anticoagulation | UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-08-27 | — | — | US | disclosed |