Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14263632 | 0.93 | CA12 (0.47) | CA12CA2CA3CA4CA6 | |
| SCHEMBL15214946 | 0.82 | ALDH1A1 (0.38) | CA12CA2CA3CA4CA6 | |
| SCHEMBL12794518 | 0.81 | CA12 (0.57) | CA12CA2CA3CA4CA6 | |
| SCHEMBL15444951 | 0.81 | CA12 (0.57) | CA12CA2CA3CA4CA6 | |
| SCHEMBL82581 | 0.81 | CA12 (0.57) | CA12CA2CA3CA4CA6 | |
| SCHEMBL28359584 | 0.77 | CA12 (0.53) | CA12CA2CA3CA4CA6 | |
| SCHEMBL30952353 | 0.77 | CA12 (0.53) | CA12CA2CA3CA4CA6 | |
| SCHEMBL1701925 | 0.76 | ALDH1A1 (0.31) | CA12CA2CA3CA4CA6 | |
| SCHEMBL15334 | 0.76 | — | — | |
| SCHEMBL4658729 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140044671-A1 | AMINE CONDENSATION POLYMERS AS PHOSPHATE SEQUESTRANTS | GENZYME CORPORATION (US) | 2014-02-13 | — | — | US | disclosed |
| US-20120288471-A1 | Amine Condensation Polymers as Phosphate Sequestrants | GENZYME CORPORATION (US) | 2012-11-15 | — | — | US | disclosed |
| US-20100254935-A1 | Amine condensation polymers as phosphate sequestrants | GENZYME CORPORATION (US) | 2010-10-07 | — | — | US | disclosed |
| US-20080085259-A1 | Amine condensation polymers as phosphate sequestrants | GENZYME CORPORATION | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140044671-A1 | AMINE CONDENSATION POLYMERS AS PHOSPHATE SEQUESTRANTS | PHPT1, CEPT1, PNMT | CA12 2690/4885CA2 1605/4885CA3 3642/4885 |
| US-20080085259-A1 | Amine condensation polymers as phosphate sequestrants | PHPT1, CEPT1, PNMT | CA12 2690/4885CA2 1605/4885CA3 3642/4885 |
| US-20120288471-A1 | Amine Condensation Polymers as Phosphate Sequestrants | PHPT1, CEPT1, PNMT | CA12 2690/4885CA2 1605/4885CA3 3642/4885 |
| US-20100254935-A1 | Amine condensation polymers as phosphate sequestrants | PHPT1, CEPT1, PNMT | CA12 2690/4885CA2 1605/4885CA3 3642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.