SCHEMBL15216341

SCHEMBL15216341

COc1ccc2c(-c3cccc4ccccc34)c3ccccc3c(-c3ccc(-c4cc(-c5ccccc5)cc(-c5ccccc5)c4)cc3)c2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.43
ABCB1 P08183 1/20 0.43
BCR P11274 1/20 0.43
CYP2C9 P11712 4/20 0.43
CYP2C19 P33261 4/20 0.43
CYP11B1 P15538 3/20 0.43
CYP11B2 P19099 3/20 0.43
CYP1A2 P05177 3/20 0.43
CYP3A4 P08684 3/20 0.43
CYP2D6 P10635 3/20 0.43
CYP2B6 P20813 2/20 0.43
ACACA Q13085 1/20 0.42
ALOX5 P09917 3/20 0.41
GPR84 Q9NQS5 2/20 0.40
KCNA5 P22460 1/20 0.40
KCNH2 Q12809 1/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2620616 0.96 CYP1A2 (0.41) ABL1ABCB1BCRCYP2C9CYP2C19
SCHEMBL18000025 0.90 ACACA (0.47) ABL1ABCB1BCRCYP2C9CYP2C19
SCHEMBL18103855 0.86 PPARG (0.36) ABL1ABCB1BCRCYP2C9CYP2C19
SCHEMBL14363721 0.85 CYP1A2 (0.44) ABL1ABCB1BCRCYP2C9CYP2C19
SCHEMBL9613076 0.85 ENPP1 (0.48) ABL1ABCB1BCRCYP2C9CYP2C19
SCHEMBL14363733 0.85 KCNA5 (0.50) CYP2C9CYP2C19CYP11B1CYP11B2CYP1A2
SCHEMBL12331009 0.84 CYP11B2 (0.57) ABL1ABCB1BCRCYP2C9CYP2C19
SCHEMBL23879787 0.82 CA12 (0.43) ALOX5GPR84KDM4EALDH1A1MAPT
SCHEMBL24922893 0.82 CA12 (0.43) ALOX5GPR84KDM4EALDH1A1MAPT
SCHEMBL27953243 0.82 CYP1A2 (0.48) CYP2C9CYP2C19CYP11B1CYP11B2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130221333-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2013-08-29 US disclosed
US-20130221333-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2013-08-29 US disclosed