Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.54 |
| ▸ | THRB | P10828 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | APAF1 | O14727 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GSR | P00390 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10035109 | 0.76 | MEN1 (0.55) | ABCB1THRBRECQLTDP1MEN1 | |
| SCHEMBL10035120 | 0.72 | ABCB1 (0.61) | ABCB1THRBRECQLTDP1MAPK1 | |
| SCHEMBL30272256 | 0.64 | ABCB1 (0.59) | ABCB1THRBRECQLTDP1MAPK1 | |
| SCHEMBL10035114 | 0.63 | MEN1 (0.53) | ABCB1THRBRECQLTDP1MEN1 | |
| SCHEMBL18680519 | 0.63 | APP (0.59) | ABCB1THRBRECQLTDP1MAPK1 | |
| Hydrochloric Acid SCHEMBL31656268 | 0.62 | MAPT (0.60) | ABCB1THRBRECQLTDP1MAPK1 | |
| Methylene Blue Cation SCHEMBL127316 | 0.61 | APP (1.00) | ABCB1THRBRECQLTDP1MAPK1 | |
| Methylene Blue Cation SCHEMBL29441543 | 0.61 | APP (1.00) | ABCB1THRBRECQLTDP1MAPK1 | |
| SCHEMBL18680530 | 0.61 | ABCB1 (0.46) | ABCB1THRBRECQLTDP1MAPK1 | |
| Methylene Blue Cation SCHEMBL4227551 | 0.61 | APP (1.00) | ABCB1THRBRECQLTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9651490-B2 | Amine-substituted tricyclic fluorescent dyes | ATTO-TEC GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| US-9651490-B2 | Amine-substituted tricyclic fluorescent dyes | ATTO-TEC GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| US-20130224871-A1 | Novel Amine-Substituted Tricyclic Fluorescent Dyes | ATTO-TEC GMBH (DE) | 2013-08-29 | — | — | US | disclosed |
| US-20130224871-A1 | Novel Amine-Substituted Tricyclic Fluorescent Dyes | ATTO-TEC GMBH (DE) | 2013-08-29 | — | — | US | disclosed |