Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methylene Blue Cation. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 9/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | THRB | P10828 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 4/20 | 1.00 |
| ▸ | RECQL | P46063 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | BLM | P54132 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | ATM | Q13315 | 3/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | APAF1 | O14727 | 2/20 | 1.00 |
| ▸ | GSR | P00390 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | MAOA | P21397 | 2/20 | 1.00 |
| ▸ | PPARG | P37231 | 2/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Blue Cation SCHEMBL29441543 | 1.00 | APP (1.00) | APPMAPTTHRBMAPK1RECQL | |
| Methylene Blue Cation SCHEMBL4227551 | 0.99 | APP (1.00) | APPMAPTTHRBMAPK1RECQL | |
| Methylene Blue Cation SCHEMBL29668541 | 0.97 | THRB (1.00) | APPMAPTTHRBMAPK1RECQL | |
| Methylene Blue Cation SCHEMBL29357640 | 0.97 | THRB (1.00) | APPMAPTTHRBMAPK1RECQL | |
| Methylene Blue Cation SCHEMBL30021960 | 0.97 | APP (0.97) | APPMAPTTHRBMAPK1RECQL | |
| Methylene Blue Cation SCHEMBL30664737 | 0.97 | THRB (1.00) | APPMAPTTHRBMAPK1RECQL | |
| Methylene Blue Cation SCHEMBL29389009 | 0.97 | THRB (1.00) | APPMAPTTHRBMAPK1RECQL | |
| SCHEMBL13116706 | 0.90 | APP (0.81) | APPMAPTTHRBMAPK1RECQL | |
| SCHEMBL14271006 | 0.90 | APP (0.81) | APPMAPTTHRBMAPK1RECQL | |
| SCHEMBL18070252 | 0.87 | APP (0.77) | APPMAPTTHRBMAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7402 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772170-B | Dihydroxanthene chemiluminescent group and preparation method and application thereof | PEKING UNIVERSITY SHENZHEN GRADUATE SCHOOL (CN) | 2026-05-26 | — | — | CN | claimed |
| US-20260137815-A1 | DIAGNOSTIC AND TREATMENT METHODS FOR ONYCHOMYCOSIS | TOEFX INC (CA) | 2026-05-21 | — | — | US | claimed |
| CN-116559257-B | Ratio type DNA electrochemical sensor for accurate determination of swing type base pair genotyping | 福建医科大学附属第一医院 | 2026-05-12 | — | — | CN | claimed |
| CN-118169198-B | Preparation method and application of photoelectrochemistry-surface-enhanced Raman dual-mode integrated sensor | 江苏大学 | 2026-05-12 | — | — | CN | claimed |
| US-20260118352-A1 | NANOCOMPOSITES AND METHODS FOR NUCLEIC ACID DETECTION, QUANTITATION AND CHARACTERIZATION | iNSAiT Biotronics Incorporated (TW) | 2026-04-30 | — | — | US | claimed |
| EP-4731795-A2 | SELECTIVE MULTIPLEXED ELECTROCHEMICAL PLATFORM FOR DETECTION OF HIV INFECTION | University of Maryland, Baltimore (US) | 2026-04-29 | — | — | EP | claimed |
| EP-3666294-B1 | POROUS OBJECT BASED ON BIOPOLYMERS HAVING A FLEXIBLE PORE SIZE, ITS PREPARATION AND USE THEREOF | Valeopharm GmbH (DE) | 2026-04-29 | — | — | EP | claimed |
| EP-4730463-A1 | LIQUID ELECTROLYTE COMPRISING SULFONAMIDE AND AT LEAST TWO LITHIUM SALTS, AND USES THEREOF | Basquevolt S.A.U. (ES) | 2026-04-22 | — | — | EP | claimed |
| US-12606725-B2 | Adhesive tape roll with color-changing dye | KORAVOS DAVID FRANKLIN (US) | 2026-04-21 | — | — | US | claimed |
| US-20260106224-A1 | LIQUID ELECTROLYTE COMPRISING SULFONAMIDE AND AT LEAST TWO LITHIUM SALTS, AND USES THEREOF | BASQUEVOLT S A (ES) | 2026-04-16 | — | — | US | claimed |
| WO-2022065942-A1 | COMPOSITION FOR COATING MEDICAL DEVICE | 가톨릭대학교 산학협력단 | 2022-03-31 | — | — | WO | claimed |
| US-20220102758-A1 | BATTERY | GELION TECHNOLOGIES PTY LTD (AU) | 2022-03-31 | — | — | US | claimed |
| CN-111175365-B | Electrochemical sensor for detecting exosome miRNA (micro ribonucleic acid), and preparation and application thereof | 重庆医科大学 | 2022-03-25 | — | — | CN | claimed |
| CN-110713666-B | Chlorine-containing rubber composition and application and preparation method thereof | 杭州星庐科技有限公司 | 2022-03-18 | — | — | CN | claimed |
| US-20220082500-A1 | TISSUE PHANTOMS | UNIVERSITY HEALTH NETWORK (CA) | 2022-03-17 | — | — | US | claimed |
| CN-114166825-A | MXene probe applied to Surface Enhanced Raman Spectroscopy (SERS) immunoassay | 佛山复星禅诚医院有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-114073982-A | Synthesis method of zinc oxide and perylene bisimide composite photocatalytic material with excellent photocatalytic performance under sunlight illumination | 新疆大学 | 2022-02-22 | — | — | CN | claimed |
| CN-107072884-B | Root canal disinfection based on photochemically activated microbubbles | 西亚克特有限责任公司 | 2022-02-08 | — | — | CN | claimed |
| US-11242450-B2 | Rubber composition, processing method thereof, and flame-retardant product using the same | HANGZHOU XINGLU TECHNOLOGIES CO., LTD (CN) | 2022-02-08 | — | — | US | claimed |
| US-20220026773-A1 | MULTICOLOR, SINGLE ACTIVE LAYER ELECTROCHROMIC DEVICES | UNIVERSITY OF SOUTH FLORIDA (US) | 2022-01-27 | — | — | US | claimed |