Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.61 |
| ▸ | THRB | P10828 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TST | Q16762 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | BLM | P54132 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | APAF1 | O14727 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15216731 | 0.72 | ABCB1 (0.54) | ABCB1THRBRECQLTDP1MAPK1 | |
| SCHEMBL18680519 | 0.68 | APP (0.59) | ABCB1THRBRECQLTDP1MAPK1 | |
| Hydrochloric Acid SCHEMBL31656268 | 0.67 | MAPT (0.60) | ABCB1THRBRECQLTDP1MAPK1 | |
| Methylene Blue Cation SCHEMBL29357640 | 0.67 | THRB (1.00) | ABCB1THRBRECQLTDP1MAPK1 | |
| Methylene Blue Cation SCHEMBL29668541 | 0.67 | THRB (1.00) | ABCB1THRBRECQLTDP1MAPK1 | |
| Methylene Blue Cation SCHEMBL30664737 | 0.67 | THRB (1.00) | ABCB1THRBRECQLTDP1MAPK1 | |
| Methylene Blue Cation SCHEMBL29389009 | 0.67 | THRB (1.00) | ABCB1THRBRECQLTDP1MAPK1 | |
| Methylene Blue Cation SCHEMBL29441543 | 0.66 | APP (1.00) | ABCB1THRBRECQLTDP1MAPK1 | |
| Methylene Blue Cation SCHEMBL127316 | 0.66 | APP (1.00) | ABCB1THRBRECQLTDP1MAPK1 | |
| SCHEMBL18680530 | 0.65 | ABCB1 (0.46) | ABCB1THRBRECQLTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9651490-B2 | Amine-substituted tricyclic fluorescent dyes | ATTO-TEC GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| US-9651490-B2 | Amine-substituted tricyclic fluorescent dyes | ATTO-TEC GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| US-20130224871-A1 | Novel Amine-Substituted Tricyclic Fluorescent Dyes | ATTO-TEC GMBH (DE) | 2013-08-29 | — | — | US | disclosed |
| US-20130224871-A1 | Novel Amine-Substituted Tricyclic Fluorescent Dyes | ATTO-TEC GMBH (DE) | 2013-08-29 | — | — | US | disclosed |
| WO-2012052435-A1 | NOVEL AMINE-SUBSTITUTED TRICYCLIC FLUORESCENT DYES | ATTO-TEC GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |