Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.72 |
| ▸ | MEN1 | O00255 | 10/20 | 0.72 |
| ▸ | GAA | P10253 | 7/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | GFER | P55789 | 3/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | THRB | P10828 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | ALPG | P10696 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13576573 | 0.90 | MAPT (0.88) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL9790530 | 0.85 | KMT2A (0.76) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL14832052 | 0.83 | L3MBTL1 (0.53) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL10172988 | 0.83 | MAPT (0.77) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL14832051 | 0.83 | L3MBTL1 (0.53) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL23928590 | 0.82 | MAPT (0.76) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL22095308 | 0.82 | MAPT (0.76) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL22095307 | 0.82 | MAPT (0.76) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL15217657 | 0.81 | MAPT (0.59) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL10807229 | 0.81 | MAPT (0.70) | MAPTKMT2AMEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630481-B1 | A method and kit for detecting alkylating agents | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2017-09-13 | — | — | EP | disclosed |
| US-20130224876-A1 | A METHOD AND DEVICE FOR DETECTING ALKYLATING AGENTS | Univeristy College Cardiff Consultants Limited | 2013-08-29 | — | — | US | disclosed |