Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.76 |
| ▸ | MEN1 | O00255 | 10/20 | 0.76 |
| ▸ | GAA | P10253 | 7/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.76 |
| ▸ | HTT | P42858 | 3/20 | 0.76 |
| ▸ | GFER | P55789 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | THRB | P10828 | 3/20 | 0.74 |
| ▸ | NPC1 | O15118 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.74 |
| ▸ | ALPI | P09923 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | ALPG | P10696 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22095308 | 1.00 | MAPT (0.76) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL23928590 | 1.00 | MAPT (0.76) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL9790530 | 0.94 | KMT2A (0.76) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL13576573 | 0.92 | MAPT (0.88) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL10172988 | 0.85 | MAPT (0.77) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL4877431 | 0.84 | MAPT (0.69) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL4877424 | 0.84 | MAPT (0.69) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL15217655 | 0.82 | MAPT (0.72) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL23928614 | 0.82 | MAPT (1.00) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL31483978 | 0.82 | MAPT (0.60) | MAPTKMT2AMEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123855-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | UNIVERSITY OF WASHINGTON (US) | 2020-06-18 | — | — | WO | disclosed |