SCHEMBL15217690

SCHEMBL15217690

CC1=CC(=O)OC2C=C(O)C=CC12

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15343497 0.83 LMNA (0.32) LMNAGAA
SCHEMBL15343495 0.80 LMNA (0.30) LMNAGAA
SCHEMBL15339825 0.80
SCHEMBL15339820 0.79
SCHEMBL14458078 0.77 LMNA (0.33) LMNAGAA
SCHEMBL15343499 0.76
SCHEMBL15343500 0.73
SCHEMBL12825236 0.69
SCHEMBL15339816 0.69
SCHEMBL15339824 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9249128-B2 Anti-cancer serine hydrolase inhibitory carbamates THE SCRIPPS RESEARCH INSTITUTE (US) 2016-02-02 US disclosed
US-9140836-B2 Method of shielding ultraviolet light and increasing visible light, and ultraviolet-light-shielding and visible-light-increasing material which enables implementation of the method TELEFONAKTIEBOLAGET L M ERICSSON (PUBL) (SE) 2015-09-22 US disclosed
US-9140836-B2 Method of shielding ultraviolet light and increasing visible light, and ultraviolet-light-shielding and visible-light-increasing material which enables implementation of the method TELEFONAKTIEBOLAGET L M ERICSSON (PUBL) (SE) 2015-09-22 US disclosed
US-20130281453-A1 ANTI-CANCER SERINE HYDROLASE INHIBITORY CARBAMATES THE SCRIPPS RESEARCH INSTITUTE (US) 2013-10-24 US disclosed
US-20130221239-A1 METHOD OF SHIELDING ULTRAVIOLET LIGHT AND INCREASING VISIBLE LIGHT, AND ULTRAVIOLET-LIGHT-SHIELDING AND VISIBLE-LIGHT-INCREASING MATERIAL WHICH ENABLES IMPLEMENTATION OF THE METHOD TELEFONAKTIEBOLAGET L M ERICSSON (PUBL) (SE) 2013-08-29 US disclosed
US-20130221239-A1 METHOD OF SHIELDING ULTRAVIOLET LIGHT AND INCREASING VISIBLE LIGHT, AND ULTRAVIOLET-LIGHT-SHIELDING AND VISIBLE-LIGHT-INCREASING MATERIAL WHICH ENABLES IMPLEMENTATION OF THE METHOD TELEFONAKTIEBOLAGET L M ERICSSON (PUBL) (SE) 2013-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130281453-A1 ANTI-CANCER SERINE HYDROLASE INHIBITORY CARBAMATES AADAC, DDAH1, PRSS1 LMNA 4450/4885GAA 1240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.