SCHEMBL15218273

SCHEMBL15218273

Cc1ccc(S(=O)(=O)COCC(COCO)(COCO)COCO)cc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
KMT2A Q03164 5/20 0.46
MEN1 O00255 1/20 0.46
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
LMNA P02545 2/20 0.39
RECQL P46063 1/20 0.39
PAX8 Q06710 2/20 0.38
MAPT P10636 1/20 0.38
ADAM17 P78536 1/20 0.38
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15218271 0.84 CA1 (0.38) ALDH1A1KMT2AMEN1CYP3A4CYP2C9
SCHEMBL12858351 0.75 C5AR1 (0.37) ALDH1A1KMT2AMEN1CYP3A4CYP2C9
SCHEMBL21331009 0.74 ALDH1A1 (0.53) ALDH1A1KMT2AMEN1CYP3A4CYP2C9
SCHEMBL20787718 0.70 GAA (0.42) ALDH1A1KMT2AMEN1CYP3A4CYP2C9
SCHEMBL23555194 0.70 ALDH1A1 (0.57) ALDH1A1KMT2AMEN1CYP3A4CYP2C9
SCHEMBL4846711 0.69 ALDH1A1 (0.61) ALDH1A1KMT2AMEN1CYP3A4CYP2C9
SCHEMBL6889902 0.69 ALDH1A1 (0.51) ALDH1A1KMT2AMEN1CYP3A4CYP2C9
SCHEMBL9107528 0.69 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1CYP3A4CYP2C9
SCHEMBL16622648 0.69 ALDH1A1 (0.55) ALDH1A1KMT2AMEN1CYP3A4CYP2C9
SCHEMBL25986593 0.68 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130225789-A1 Polyethylene Glycol Having Hetero Multiple Functional Groups SUN YI (US) 2013-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130225789-A1 Polyethylene Glycol Having Hetero Multiple Functional Groups CLTB, GMFG, HDGF ALDH1A1 3374/4885KMT2A 4114/4885MEN1 4263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.