Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15218272 | 0.86 | TDP1 (0.35) | TDP1MEN1GAAKMT2A | |
| SCHEMBL16923544 | 0.78 | TDP1 (0.55) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL3177993 | 0.74 | TDP1 (0.46) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL22939663 | 0.74 | TDP1 (0.46) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL17779920 | 0.73 | TDP1 (0.58) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL16923542 | 0.73 | TDP1 (0.44) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL14978979 | 0.73 | MEN1 (0.46) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL8983076 | 0.73 | TDP1 (0.44) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL21311602 | 0.71 | TDP1 (0.43) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL16013856 | 0.71 | TDP1 (0.43) | TDP1MEN1GAAKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130225789-A1 | Polyethylene Glycol Having Hetero Multiple Functional Groups | SUN YI (US) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225789-A1 | Polyethylene Glycol Having Hetero Multiple Functional Groups | CLTB, GMFG, HDGF | TDP1 4516/4885MEN1 4263/4885GAA 1078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.