Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.79 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.73 |
| ▸ | TUBB | P07437 | 1/20 | 0.73 |
| ▸ | YES1 | P07947 | 1/20 | 0.73 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.73 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.73 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.73 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.73 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.73 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.73 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.73 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.73 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.73 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.73 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.73 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.73 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.73 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.73 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.72 |
| ▸ | MAOB | P27338 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16438105 | 0.90 | MAOB (0.73) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| Butin SCHEMBL29929348 | 0.88 | CYP19A1 (1.00) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| Butin SCHEMBL68554 | 0.88 | CYP19A1 (1.00) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| Butin SCHEMBL29929512 | 0.88 | CYP19A1 (1.00) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| Butin SCHEMBL5504140 | 0.88 | CYP19A1 (1.00) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| SCHEMBL14490032 | 0.85 | CYP19A1 (0.84) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| Liquirtigenin SCHEMBL29552383 | 0.85 | CYP19A1 (1.00) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| Liquirtigenin SCHEMBL1071066 | 0.85 | CYP19A1 (1.00) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| Liquirtigenin SCHEMBL30352791 | 0.85 | CYP19A1 (1.00) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| Liquirtigenin SCHEMBL26970367 | 0.85 | CYP19A1 (1.00) | CYP19A1TUBB4ATUBBYES1TUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-9539189-B2 | Photoprotective personal care composition | CONOPCO, INC. (US) | 2017-01-10 | — | — | US | disclosed |
| US-20160193126-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN INC (US) | 2016-07-07 | — | — | US | disclosed |
| US-20160081896-A1 | PHOTOPROTECTIVE PERSONAL CARE COMPOSITION | Conopco, In., d/b/a UNILEVER (US) | 2016-03-24 | — | — | US | disclosed |
| US-9126913-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-20140371491-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN, INC. (US) | 2014-12-18 | — | — | US | disclosed |
| US-8729136-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2014-05-20 | — | — | US | disclosed |
| US-20130224135-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | UNIGEN, INC. (US) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130224135-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | TYR, DDT, HAAO | CYP19A1 203/4885TUBB4A 3512/4885TUBB 3626/4885 |
| US-20160193126-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | TYR, DDT, HAAO | CYP19A1 203/4885TUBB4A 3512/4885TUBB 3626/4885 |
| US-20160081896-A1 | PHOTOPROTECTIVE PERSONAL CARE COMPOSITION | CUTA, DSG1, ERCC1 | CYP19A1 555/4885TUBB4A 2858/4885TUBB 2091/4885 |
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | TYR, DDT, HAAO | CYP19A1 203/4885TUBB4A 3512/4885TUBB 3626/4885 |
| US-20140371491-A1 | DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES | TYR, DDT, HAAO | CYP19A1 203/4885TUBB4A 3512/4885TUBB 3626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.