⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198316 | 0.74 | — | — | |
| SCHEMBL11437332 | 0.60 | — | — | |
| SCHEMBL1727698 | 0.59 | — | — | |
| SCHEMBL19881601 | 0.58 | — | — | |
| SCHEMBL220987 | 0.57 | — | — | |
| SCHEMBL49776 | 0.57 | — | — | |
| SCHEMBL5256 | 0.57 | — | — | |
| SCHEMBL277548 | 0.57 | — | — | |
| SCHEMBL3651286 | 0.56 | — | — | |
| SCHEMBL8914404 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567443-B | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-28 | — | — | CN | disclosed |
| CN-108473496-A | heterocyclic compounds and their use | 上海亦恩生物科技有限公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-105461736-B | Inhibitors of phosphatidylinositol3 3-kinase with zinc bound site | 柯瑞斯公司 | 2018-06-12 | — | — | CN | disclosed |
| CN-107648216-A | Aromatic hydrocarbon receptor (AhR) conditioning agent as novel cancer therapy | 波士顿大学管理委员会 | 2018-02-02 | — | — | CN | disclosed |
| CN-103179968-B | Modulators of the arene receptor (AhR) as cancer therapy | 波士顿大学管理委员会 | 2017-10-03 | — | — | CN | disclosed |
| CN-107106546-A | Triazolopyridine compounds and methods for treating cystic fibrosis | 弗拉特利发现实验室有限责任公司 | 2017-08-29 | — | — | CN | disclosed |
| US-9730449-B2 | Thiazole compound and its use in pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |
| CN-106727562-A | The composition of buprenorphine and mu opioid receptor antagonists | 阿尔科米斯制药爱尔兰有限公司 | 2017-05-31 | — | — | CN | disclosed |
| EP-3093286-A1 | THIAZOLE COMPOUNDS AND PEST CONTROL APPLICATIONS THEREOF | Sumitomo Chemical Co., Ltd (JP) | 2016-11-16 | — | — | EP | disclosed |
| US-20160324155-A1 | THIAZOLE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-11-10 | — | — | US | disclosed |
| WO-2005087714-A2 | METHODS OF TREATMENT OF AMYLOIDOSIS USING BI-CYCLIC ASPARTYL PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | WO | disclosed |
| WO-2005087215-A1 | SUBSTITUTED UREA AND CARBAMATE, PHENACYL-2-HYDROXY-3-DIAMINOALKANE, AND BENZAMIDE-2-HYDROXY-3-DIAMINOALKANE ASPARTYL-PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | WO | disclosed |
| WO-2005087752-A2 | SUBSTITUTED HYDROXYETHYLAMINE ASPARTYL PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | WO | disclosed |
| WO-2005087751-A2 | SUBSTITUTED HYDROXYETHYLAMINE ASPARTYL PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | WO | disclosed |
| WO-2005070407-A1 | METHODS OF TREATMENT OF AMYLOIDOSIS USING ASPARTYL-PROTEASE INIHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2005-08-04 | — | — | WO | disclosed |
| EP-1337520-B1 | SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS | CIBA SC HOLDING AG (CH) | 2004-12-15 | — | — | EP | disclosed |
| US-6387992-B1 | HEAT, OXIDATION AND LIGHT RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-05-14 | — | — | US | disclosed |
| US-5821391-A | HYDROGENATING 1,3-DIOXANES IN THE PRESENCE OF A CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-10-13 | — | — | US | disclosed |
| US-5780686-A | REACTING 1,3-DIOXANES WITH AMMONIA AND HYDROGEN IN PRESENCE OF HYDROGENATION CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| US-5780687-A | REACTING 1,3-DIOXANES WITH HYDROGEN IN PRESENCE OF HYDROGENATION CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |