SCHEMBL15219042

SCHEMBL15219042

N=C(SN)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.52
F10 P00742 1/20 0.52
F12 P00748 1/20 0.52
F7 P08709 1/20 0.52
F3 P13726 1/20 0.52
PKM P14618 1/20 0.52
BLM P54132 2/20 0.50
PRSS1 P07477 3/20 0.48
PRSS2 P07478 3/20 0.48
PRSS3 P35030 3/20 0.48
RECQL P46063 2/20 0.48
KMT2A Q03164 2/20 0.48
C1S P09871 1/20 0.48
TSHR P16473 2/20 0.40
POLB P06746 2/20 0.40
MAPT P10636 2/20 0.40
CYP3A4 P08684 1/20 0.40
PARP1 P09874 1/20 0.40
CYP2C19 P33261 1/20 0.40
PMP22 Q01453 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL46960 0.75 F2 (0.54) F2F10F12F7F3
SCHEMBL3073023 0.75
SCHEMBL1668498 0.74 F2 (0.46) F2F10F12F7F3
Iodide SCHEMBL11260026 0.72 F2 (0.50) F2F10F12F7F3
Bromide SCHEMBL8216160 0.72 F2 (0.50) F2F10F12F7F3
Iodide SCHEMBL2241002 0.72 F2 (0.44) F2F10F12F7F3
SCHEMBL24761126 0.70 F2 (0.42) F2F10F12F7F3
SCHEMBL18557033 0.69 F2 (1.00) F2F10F12F7F3
Benzamidine SCHEMBL23067876 0.69 F2 (1.00) F2F10F12F7F3
Benzamidine SCHEMBL9207 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2074084-B1 COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR BOEHRINGER INGELHEIM INT (DE) 2013-08-28 EP disclosed