⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL11260026 | 0.97 | F2 (0.50) | — | |
| Bromide SCHEMBL8216160 | 0.97 | F2 (0.50) | — | |
| SCHEMBL15219042 | 0.75 | F2 (0.52) | — | |
| SCHEMBL2883723 | 0.73 | CA2 (0.58) | — | |
| SCHEMBL2883726 | 0.73 | CA2 (0.58) | — | |
| Benzamide SCHEMBL30081945 | 0.73 | — | — | |
| SCHEMBL16814995 | 0.73 | F2 (0.58) | — | |
| SCHEMBL6429964 | 0.73 | CA2 (0.58) | — | |
| SCHEMBL17504065 | 0.73 | CA2 (0.58) | — | |
| SCHEMBL3805878 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303546-A1 | Process And Intermediates For The Preparation Of Pyroxasulfone | ADAMA AGAN LTD. (IL) | 2023-09-28 | — | — | US | claimed |
| EP-0005385-B1 | PIPERAZINE METHANE IMINE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE | LAROCHE NAVARRON S.A. Société dite: (FR) | 1982-09-01 | — | — | EP | claimed |
| EP-0005385-A1 | Piperazine methane imine derivatives, methods for their preparation and their therapeutical use | LAROCHE NAVARRON S.A. Société dite: (FR) | 1979-11-14 | — | — | EP | claimed |
| US-12582619-B2 | Compounds, compositions, and methods for treating or ameliorating, or preventing viral infections | THOMAS JEFFERSON UNIVERSITY (US) | 2026-03-24 | — | — | US | disclosed |
| EP-4673138-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | Sionna Therapeutics Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| US-20240307325-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING OR AMELIORATING NONALCOHOLIC FATTY LIVER DISEASE AND RELATED DISEASES OR DISORDERS | UNIV JEFFERSON (US) | 2024-09-19 | — | — | US | disclosed |
| WO-2024182739-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | SIONNA THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| EP-4277898-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING OR AMELIORATING NONALCOHOLIC FATTY LIVER DISEASE AND RELATED DISEASES OR DISORDERS | Thomas Jefferson University (US) | 2023-11-22 | — | — | EP | disclosed |
| WO-2023200315-A1 | NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME | 주식회사 엘지화학 | 2023-10-19 | — | — | WO | disclosed |
| CN-110386919-B | Nuclear transport modulators and uses thereof | 卡尔约药物治疗公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-110183422-B | Nuclear transport modulators and uses thereof | 卡尔约药物治疗公司 | 2023-07-14 | — | — | CN | disclosed |
| US-6093733-A | FOR THE TREATMENT OR PREVENTION OF DISEASES THE TREATMENT OR PREVENTION OF WHICH IS MEDIATED BY MUSCARINIC RECEPTOR AGONISM; ALZHEIMER'S DISEASE | PFIZER INC. | 2000-07-25 | — | — | US | disclosed |
| EP-0805153-A1 | Novel muscarinic receptor agonists | PFIZER INC. (US) | 1997-11-05 | — | — | EP | disclosed |
| EP-0005385-B1 | PIPERAZINE METHANE IMINE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE | LAROCHE NAVARRON S.A. Société dite: (FR) | 1982-09-01 | — | — | EP | disclosed |
| US-4335043-A | Substituted N-methylene derivatives of thienamycin | MERCK & CO., INC. (US) | 1982-06-15 | — | — | US | disclosed |
| US-4259334-A | Piperazines and therapeutic utility | LAROCHE NAVARRON S.A. (FR) | 1981-03-31 | — | — | US | disclosed |
| US-4232030-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-4194047-A | Substituted N-methylene derivatives of thienamycin | MERCK & CO., INC. (US) | 1980-03-18 | — | — | US | disclosed |
| EP-0005385-A1 | Piperazine methane imine derivatives, methods for their preparation and their therapeutical use | LAROCHE NAVARRON S.A. Société dite: (FR) | 1979-11-14 | — | — | EP | disclosed |
| EP-0001264-A1 | Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | disclosed |