Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1621875 | 0.79 | NPY5R (0.52) | NPY5RHIF1AEPAS1RAB9APTGS1 | |
| SCHEMBL16358418 | 0.78 | NPY5R (0.46) | NPY5RHIF1AEPAS1PDE10ARAB9A | |
| SCHEMBL3928750 | 0.78 | RAB9A (0.58) | NPY5RRAB9APTGS1NPC1GAA | |
| SCHEMBL3661268 | 0.78 | NPY5R (0.63) | NPY5RHIF1AEPAS1PDE10ARAB9A | |
| SCHEMBL1619860 | 0.77 | CNR2 (0.51) | NPY5RHIF1AEPAS1RAB9APTGS1 | |
| SCHEMBL16358415 | 0.75 | NPC1 (0.48) | NPY5RHIF1AEPAS1RAB9APTGS1 | |
| SCHEMBL14960390 | 0.75 | NPY5R (0.47) | NPY5RRAB9APTGS1NPC1EPHX2 | |
| SCHEMBL16359181 | 0.74 | GAA (0.50) | NPY5RHIF1AEPAS1RAB9APTGS1 | |
| SCHEMBL1465583 | 0.74 | RAB9A (0.57) | NPY5RRAB9APTGS1NPC1GAA | |
| SCHEMBL14960396 | 0.74 | RAB9A (0.46) | NPY5RHIF1AEPAS1RAB9APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-B1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2013-08-28 | — | — | EP | disclosed |