Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | IDH2 | P48735 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 1/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1621477 | 0.80 | CNR2 (0.53) | CYP3A4CYP2C19POLBRAB9ALMNA | |
| SCHEMBL16358735 | 0.79 | CYP3A4 (0.44) | CYP3A4CYP2C19POLBRAB9ALMNA | |
| SCHEMBL965744 | 0.76 | LMNA (0.55) | POLBLMNATHRBALDH1A1IDH2 | |
| SCHEMBL30977683 | 0.72 | TP53 (0.65) | CYP3A4CYP2C19RAB9ALMNAALDH1A1 | |
| SCHEMBL4455493 | 0.72 | TP53 (0.65) | CYP3A4CYP2C19RAB9ALMNAALDH1A1 | |
| SCHEMBL1621632 | 0.71 | CNR2 (0.53) | CYP3A4CYP2C19LMNAALDH1A1CYP2C9 | |
| SCHEMBL13842707 | 0.71 | RAB9A (0.53) | CYP3A4CYP2C19POLBRAB9ALMNA | |
| SCHEMBL965745 | 0.70 | CNR2 (0.55) | LMNAALDH1A1IDH2CNR2GAA | |
| SCHEMBL15219041 | 0.70 | MAPK14 (0.42) | LMNAIDH2KMT2ATRPV4UBE2M | |
| SCHEMBL23060409 | 0.70 | MEN1 (0.65) | RAB9AALDH1A1EPHX2KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-B1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2013-08-28 | — | — | EP | disclosed |