Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.41 |
| ▸ | ACE | P12821 | 3/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.40 |
| ▸ | TPH1 | P17752 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8227873 | 1.00 | MME (0.51) | MMEPPARGPPARAMGLLSLC1A3 | |
| SCHEMBL14598295 | 0.85 | MME (0.54) | MMEFFAR1ACE2ACECPA1 | |
| SCHEMBL8228374 | 0.85 | MME (0.54) | MMEFFAR1ACE2ACECPA1 | |
| SCHEMBL20976910 | 0.85 | MME (0.54) | MMEFFAR1ACE2ACECPA1 | |
| SCHEMBL8227650 | 0.84 | PPARA (0.51) | MMEPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL8227806 | 0.84 | MME (0.50) | MMEPPARGPPARAL3MBTL1ACE2 | |
| SCHEMBL8256402 | 0.84 | MME (0.50) | MMEACE2ACECPA1ITGB1 | |
| SCHEMBL15219919 | 0.84 | MME (0.50) | MMEPPARGPPARAL3MBTL1ACE2 | |
| SCHEMBL13227726 | 0.82 | PPARG (0.51) | PPARGPPARAITGB1ITGA4ACACB | |
| SCHEMBL12568310 | 0.81 | MME (0.40) | MMEPPARGPPARAL3MBTL1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084182-B1 | ANTIDIABETIC COMPOUNDS | CADILA HEALTHCARE LTD (IN) | 2013-08-28 | — | — | EP | disclosed |