Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SDCBP | O00560 | 1/20 | 0.43 |
| ▸ | SDC2 | P34741 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8227806 | 1.00 | MME (0.50) | MMEPPARGPPARAALDH1A1MAPT | |
| SCHEMBL12568310 | 0.88 | MME (0.40) | MMEPPARGPPARAALDH1A1MAPT | |
| SCHEMBL8227873 | 0.84 | MME (0.51) | MMEPPARGPPARAL3MBTL1ACE | |
| SCHEMBL15219916 | 0.84 | MME (0.51) | MMEPPARGPPARAL3MBTL1ACE | |
| SCHEMBL8228374 | 0.84 | MME (0.54) | MMEACECPA1ACE2 | |
| SCHEMBL20976910 | 0.84 | MME (0.54) | MMEACECPA1ACE2 | |
| SCHEMBL14598295 | 0.84 | MME (0.54) | MMEACECPA1ACE2 | |
| SCHEMBL8227650 | 0.83 | PPARA (0.51) | MMEPPARGPPARAKMT2AACE | |
| SCHEMBL8256402 | 0.83 | MME (0.50) | MMEHCAR2ACECPA1ACE2 | |
| SCHEMBL15219915 | 0.83 | MME (0.53) | MMEPPARGPPARAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084182-B1 | ANTIDIABETIC COMPOUNDS | CADILA HEALTHCARE LTD (IN) | 2013-08-28 | — | — | EP | disclosed |