SCHEMBL8227650

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8229993	0.89	PPARA (0.52)	PPARAPPARGKMT2AITGB1ITGA4
	SCHEMBL8227873	0.84	MME (0.51)	PPARAPPARGITGB1ITGA4ITGB7
	SCHEMBL15219916	0.84	MME (0.51)	PPARAPPARGITGB1ITGA4ITGB7
	SCHEMBL20976910	0.84	MME (0.54)	MMEACECPA1ACE2FFAR1
	SCHEMBL14598295	0.84	MME (0.54)	MMEACECPA1ACE2FFAR1
	SCHEMBL8228374	0.84	MME (0.54)	MMEACECPA1ACE2FFAR1
	SCHEMBL8227806	0.83	MME (0.50)	PPARAPPARGKMT2AMMEACE
	SCHEMBL15219919	0.83	MME (0.50)	PPARAPPARGKMT2AMMEACE
	SCHEMBL8256402	0.83	MME (0.50)	ITGB1ITGA4ITGB7MMEACE
	SCHEMBL8229994	0.83	JAK1 (0.46)	PPARAPPARGMMEACECPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.