Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12632572 | 0.85 | HSP90AA1 (0.60) | CYP3A4TSHRSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL25519810 | 0.81 | TAAR1 (0.61) | CYP3A4CALM1TAAR1CYP1A2SIGMAR1 | |
| SCHEMBL30101707 | 0.81 | TAAR1 (0.61) | CYP3A4CALM1TAAR1CYP1A2SIGMAR1 | |
| SCHEMBL4885125 | 0.79 | TRPM8 (0.62) | CYP3A4SMN1; SMN2RAB9ATRPM8ALDH1A1 | |
| SCHEMBL4885116 | 0.79 | TRPM8 (0.62) | CYP3A4SMN1; SMN2RAB9ATRPM8ALDH1A1 | |
| SCHEMBL7406 | 0.78 | CYP3A4 (0.62) | CYP3A4CALM1TSHRSMN1; SMN2LMNA | |
| SCHEMBL29364835 | 0.78 | CYP3A4 (0.62) | CYP3A4CALM1TSHRSMN1; SMN2LMNA | |
| SCHEMBL29261909 | 0.78 | TAAR1 (0.61) | CYP3A4CALM1TAAR1TRPM8ALDH1A1 | |
| SCHEMBL24883650 | 0.78 | TAAR1 (0.53) | CYP3A4CALM1TSHRTAAR1TRPM8 | |
| SCHEMBL9425769 | 0.78 | TRPM8 (0.67) | CYP3A4CALM1SMN1; SMN2RAB9ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2529632-B1 | Cinnamic acid amides as spicy flavour agents | SYMRISE AG (DE) | 2013-08-28 | — | — | EP | disclosed |