Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.67 |
| ▸ | CTSL | P07711 | 2/20 | 0.63 |
| ▸ | CTSS | P25774 | 1/20 | 0.63 |
| ▸ | CTSK | P43235 | 1/20 | 0.63 |
| ▸ | CCKBR | P32239 | 6/20 | 0.59 |
| ▸ | CCKAR | P32238 | 1/20 | 0.58 |
| ▸ | TACR1 | P25103 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27902194 | 0.93 | ACE (0.71) | ACECTSLCTSSCTSKCCKBR | |
| SCHEMBL30643016 | 0.93 | ACE (0.71) | ACECTSLCTSSCTSKCCKBR | |
| SCHEMBL27902195 | 0.93 | ACE (0.71) | ACECTSLCTSSCTSKCCKBR | |
| SCHEMBL15220151 | 0.93 | CTSL (0.65) | ACECTSLCTSSCTSKCCKBR | |
| SCHEMBL15220261 | 0.92 | MAPT (0.61) | ACECTSLCTSSCTSKCCKBR | |
| SCHEMBL8251244 | 0.91 | ACE (0.64) | ACECTSLCTSSCTSKCCKBR | |
| SCHEMBL3468049 | 0.89 | ACE (0.66) | ACECTSLCTSSCTSKCCKBR | |
| SCHEMBL3468048 | 0.89 | ACE (0.66) | ACECTSLCTSSCTSKCCKBR | |
| SCHEMBL8257450 | 0.89 | ACE (0.66) | ACECTSLCTSSCTSKCCKBR | |
| SCHEMBL27893082 | 0.88 | ACE (0.64) | ACECTSLCTSSCTSKCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1865950-B1 | COMPOUNDS USEFUL AS MODULATORS OF THE PROTEASOME ACTIVITY | CENTRE NAT RECH SCIENT (FR) | 2013-08-28 | — | — | EP | disclosed |