SCHEMBL15224181

SCHEMBL15224181

COc1cc(C=Cc2ccc(OC3CCCCO3)cc2)cc(OC)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.54
NQO2 P16083 4/20 0.54
CYP1A1 P04798 4/20 0.54
CYP1B1 Q16678 4/20 0.54
AHR P35869 3/20 0.54
ABL1 P00519 2/20 0.54
TTR P02766 2/20 0.54
ABCB1 P08183 2/20 0.54
ALOX5 P09917 2/20 0.54
BCR P11274 2/20 0.54
CYP19A1 P11511 2/20 0.54
PTGS2 P35354 2/20 0.54
CYP1A2 P05177 2/20 0.54
TUBB4A P04350 1/20 0.54
TUBB P07437 1/20 0.54
TUBA3C P0DPH7 1/20 0.54
TUBA1B P68363 1/20 0.54
TUBA4A P68366 1/20 0.54
TUBB4B P68371 1/20 0.54
TUBB3 Q13509 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3360303 0.85 CYP1A1 (0.58) ESR1NQO2CYP1A1CYP1B1AHR
SCHEMBL3360306 0.85 CYP1A1 (0.58) ESR1NQO2CYP1A1CYP1B1AHR
SCHEMBL3358376 0.83 PDE4B (0.46) ESR1NQO2CYP1A1CYP1B1AHR
SCHEMBL3358380 0.83 PDE4B (0.46) ESR1NQO2CYP1A1CYP1B1AHR
SCHEMBL813805 0.83 NPC1 (0.46) CYP19A1KDM4EMEN1NPC1GAA
SCHEMBL3358346 0.79 PTPN1 (0.46) NQO2CYP1A1CYP1B1ABL1TTR
SCHEMBL3358340 0.79 PTPN1 (0.46) NQO2CYP1A1CYP1B1ABL1TTR
SCHEMBL9876349 0.79 KDM4E (0.39) KDM4EMEN1NPC1RAB9AKMT2A
SCHEMBL25196646 0.78 F3 (0.61) CYP1A1CYP1B1CYP1A2MAOAMAOB
SCHEMBL21527703 0.78 F3 (0.61) CYP1A1CYP1B1CYP1A2MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8524782-B2 Key intermediate for the preparation of Stilbenes, solid forms of Pterostilbene, and methods for making the same LAURUS LABS PRIVATE LIMITED (IN) 2013-09-03 US disclosed