SCHEMBL3358376

SCHEMBL3358376

COc1cc(/C=C/c2ccc(OC3CCCCO3)c(Cl)c2)cc(OC)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.46
NQO2 P16083 7/20 0.46
CYP1A1 P04798 4/20 0.46
CYP1B1 Q16678 4/20 0.46
TTR P02766 3/20 0.46
ABCG2 Q9UNQ0 1/20 0.46
MYC P01106 1/20 0.46
ALOX5 P09917 5/20 0.43
NQO1 P15559 1/20 0.43
TUBB4A P04350 2/20 0.41
TUBB P07437 2/20 0.41
TUBA3C P0DPH7 2/20 0.41
TUBA1B P68363 2/20 0.41
TUBA4A P68366 2/20 0.41
TUBB4B P68371 2/20 0.41
TUBB3 Q13509 2/20 0.41
TUBB2A Q13885 2/20 0.41
TUBB8 Q3ZCM7 2/20 0.41
TUBA3E Q6PEY2 2/20 0.41
TUBA1A Q71U36 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3358380 1.00 PDE4B (0.46) PDE4BNQO2CYP1A1CYP1B1TTR
SCHEMBL3360303 0.88 CYP1A1 (0.58) PDE4BNQO2CYP1A1CYP1B1TTR
SCHEMBL3360306 0.88 CYP1A1 (0.58) PDE4BNQO2CYP1A1CYP1B1TTR
SCHEMBL15224181 0.83 ESR1 (0.54) NQO2CYP1A1CYP1B1TTRALOX5
SCHEMBL3362970 0.79 PDE4B (0.42) PDE4BTTRKDM4E
SCHEMBL3358346 0.78 PTPN1 (0.46) PDE4BNQO2CYP1A1CYP1B1TTR
SCHEMBL3358340 0.78 PTPN1 (0.46) PDE4BNQO2CYP1A1CYP1B1TTR
SCHEMBL3362009 0.76 NQO2 (0.72) NQO2CYP1A1CYP1B1TTRABCG2
SCHEMBL3360764 0.76 NQO2 (0.72) NQO2CYP1A1CYP1B1TTRABCG2
SCHEMBL11455772 0.75 CSNK2A1 (0.43) PDE4BTTRNPC1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010046926-A2 NOVEL STILBENE ANALOGS APTUIT LAURUS PVT LTD (IN) 2010-04-29 WO disclosed