SCHEMBL3360306

SCHEMBL3360306

COc1cc(C=Cc2ccc(OC3CCCCO3)c(OC)c2)cc(OC)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 7/20 0.58
CYP1B1 Q16678 6/20 0.58
NQO2 P16083 4/20 0.58
TTR P02766 2/20 0.58
ABCG2 Q9UNQ0 1/20 0.58
MYC P01106 1/20 0.58
PDE4B Q07343 1/20 0.53
ALOX5 P09917 3/20 0.48
NQO1 P15559 1/20 0.48
TUBB4A P04350 3/20 0.46
TUBB P07437 3/20 0.46
TUBA3C P0DPH7 3/20 0.46
TUBA1B P68363 3/20 0.46
TUBA4A P68366 3/20 0.46
TUBB4B P68371 3/20 0.46
TUBB3 Q13509 3/20 0.46
TUBB2A Q13885 3/20 0.46
TUBB8 Q3ZCM7 3/20 0.46
TUBA3E Q6PEY2 3/20 0.46
TUBA1A Q71U36 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3360303 1.00 CYP1A1 (0.58) CYP1A1CYP1B1NQO2TTRABCG2
SCHEMBL3358376 0.88 PDE4B (0.46) CYP1A1CYP1B1NQO2TTRABCG2
SCHEMBL3358380 0.88 PDE4B (0.46) CYP1A1CYP1B1NQO2TTRABCG2
SCHEMBL15224181 0.85 ESR1 (0.54) CYP1A1CYP1B1NQO2TTRALOX5
SCHEMBL3358346 0.85 PTPN1 (0.46) CYP1A1CYP1B1NQO2TTRABCG2
SCHEMBL3358340 0.85 PTPN1 (0.46) CYP1A1CYP1B1NQO2TTRABCG2
SCHEMBL24366316 0.83 PDE4B (0.55) CYP1A1CYP1B1PDE4BCYP1A2CYP19A1
SCHEMBL24588569 0.83 PDE4B (0.51) PDE4BCYP1A2
SCHEMBL667201 0.83 ALDH1A1 (0.54) TTRPDE4B
SCHEMBL24367560 0.81 KDM4E (0.60) PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010046926-A2 NOVEL STILBENE ANALOGS APTUIT LAURUS PVT LTD (IN) 2010-04-29 WO claimed
WO-2010046926-A2 NOVEL STILBENE ANALOGS APTUIT LAURUS PVT LTD (IN) 2010-04-29 WO disclosed