Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15224154 | 0.80 | NPC1 (0.47) | RAB9ANPC1MEN1KMT2AEPHX1 | |
| SCHEMBL24860396 | 0.76 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL21214049 | 0.75 | MEN1 (0.52) | RAB9ANPC1MEN1KMT2AEPHX1 | |
| SCHEMBL6211416 | 0.74 | ALDH1A1 (0.39) | RAB9ANPC1MEN1KMT2AEPHX1 | |
| SCHEMBL19420693 | 0.73 | MEN1 (0.55) | RAB9ANPC1MEN1KMT2AEPHX1 | |
| SCHEMBL10907938 | 0.73 | KMT2A (0.55) | RAB9ANPC1MEN1KMT2AEPHX1 | |
| SCHEMBL11311904 | 0.73 | KMT2A (0.55) | RAB9ANPC1MEN1KMT2AEPHX1 | |
| SCHEMBL15224193 | 0.72 | MEN1 (0.48) | RAB9ANPC1MEN1KMT2AEPHX1 | |
| SCHEMBL5544335 | 0.71 | POLB (0.42) | MEN1KMT2AEPHX1ALDH1A1KDM4E | |
| SCHEMBL2734579 | 0.70 | ALDH1A1 (0.32) | MEN1KMT2AALDH1A1ECE1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524894-B2 | Inhibitor compounds of 11-beta-hydroxysteroid dehydrogenase type 1 | LABORATORIOS SALVAT, S.A. (ES) | 2013-09-03 | — | — | US | disclosed |