Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15224185 | 0.98 | PKM (0.55) | KMT2AMEN1ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL6872555 | 0.81 | EPHX2 (0.66) | ALDH1A1 | |
| SCHEMBL15224137 | 0.81 | EPHX2 (0.66) | ALDH1A1 | |
| SCHEMBL15224173 | 0.77 | CA2 (0.47) | KMT2AMEN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL19420513 | 0.76 | KMT2A (0.76) | KMT2AMEN1ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL19420702 | 0.76 | KMT2A (0.76) | KMT2AMEN1ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL15224197 | 0.75 | KMT2A (0.69) | KMT2AMEN1ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL5878791 | 0.74 | PKM (0.64) | KMT2AMEN1ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL5878686 | 0.74 | PKM (0.64) | KMT2AMEN1ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL19420646 | 0.74 | KMT2A (0.73) | KMT2AMEN1ALDH1A1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524894-B2 | Inhibitor compounds of 11-beta-hydroxysteroid dehydrogenase type 1 | LABORATORIOS SALVAT, S.A. (ES) | 2013-09-03 | — | — | US | disclosed |