Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.52 |
| ▸ | ACACB | O00763 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15224400 | 0.92 | HRH3 (0.51) | HRH3AKR1C3 | |
| SCHEMBL28555940 | 0.83 | AKR1C3 (0.41) | HRH3ACACBAKR1C3PDE10A | |
| SCHEMBL28555939 | 0.83 | AKR1C3 (0.41) | HRH3ACACBAKR1C3PDE10A | |
| SCHEMBL28547150 | 0.83 | ACACB (0.42) | HRH3ACACB | |
| SCHEMBL22491874 | 0.80 | HRH3 (0.43) | HRH3ACACB | |
| SCHEMBL22655703 | 0.80 | HRH3 (0.43) | HRH3ACACB | |
| SCHEMBL21812435 | 0.80 | ADRA1A (0.47) | HRH3ACACBAKR1C3PDE10A | |
| SCHEMBL28913940 | 0.79 | HRH3 (0.56) | HRH3 | |
| SCHEMBL578538 | 0.79 | HRH3 (0.50) | HRH3ACACBAKR1C3 | |
| SCHEMBL28547470 | 0.77 | HRH3 (0.52) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2634176-A1 | PYRIDINE DERIVATIVE AND MEDICINAL AGENT | Nippon Shinyaku Co., Ltd. (JP) | 2013-09-04 | — | — | EP | disclosed |