Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 12/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28544416 | 0.92 | DGAT2 (0.42) | ACACB | |
| SCHEMBL28541244 | 0.92 | SCD (0.41) | ACACBHRH3AOC3HMOX1 | |
| SCHEMBL28624613 | 0.84 | KDM4E (0.50) | HRH3GPR119 | |
| SCHEMBL20507912 | 0.83 | ACACB (0.44) | ACACBAOC3GRM2GRM3OPRK1 | |
| SCHEMBL21624873 | 0.83 | HRH3 (0.48) | ACACBHRH3GPR119 | |
| SCHEMBL21624876 | 0.83 | HRH3 (0.48) | ACACBHRH3GPR119 | |
| SCHEMBL15224314 | 0.83 | HRH3 (0.52) | ACACBHRH3 | |
| SCHEMBL29165956 | 0.83 | HRH3 (0.48) | ACACBHRH3GPR119 | |
| SCHEMBL28539492 | 0.78 | HRH3 (0.40) | HRH3AOC3GPR119 | |
| SCHEMBL29182795 | 0.77 | CHRNB2 (0.50) | HRH3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108135175-B | Bicyclic compounds and their use for inhibition of SUV39H2 | 肿瘤疗法科学股份有限公司 | 2021-04-06 | — | — | CN | disclosed |