Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL182987 | 1.00 | — | — | |
| Alcohol SCHEMBL1955756 | 0.96 | ALDH1A1 (0.46) | ALDH1A1TSHR | |
| Alcohol SCHEMBL1847595 | 0.89 | MEN1 (0.44) | ALDH1A1TSHR | |
| Alcohol SCHEMBL11224298 | 0.89 | MEN1 (0.44) | ALDH1A1TSHR | |
| Alcohol SCHEMBL11224304 | 0.89 | MEN1 (0.44) | ALDH1A1TSHR | |
| 2-Methoxyethanol SCHEMBL997154 | 0.85 | — | — | |
| Ethylene Glycol SCHEMBL28094818 | 0.83 | TSHR (0.42) | ALDH1A1TSHRGAA | |
| Ethylene Glycol SCHEMBL22684865 | 0.83 | TSHR (0.42) | ALDH1A1TSHRGAA | |
| Hydrogen Peroxide SCHEMBL6441406 | 0.82 | — | — | |
| Methyl Alcohol SCHEMBL1405842 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315767-B1 | PYRIDINO-PYRIDINONE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2013-09-04 | — | — | EP | disclosed |