Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 2-Methoxyethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Methoxyethanol SCHEMBL8327328 | 0.97 | ALDH1A1 (0.45) | — | |
| 2-Methoxyethanol SCHEMBL5859982 | 0.94 | ALDH1A1 (0.43) | — | |
| 2-Methoxyethanol SCHEMBL6553739 | 0.94 | ALDH1A1 (0.43) | — | |
| 2-Methoxyethanol SCHEMBL2789723 | 0.93 | — | — | |
| 2-Methoxyethanol SCHEMBL310 | 0.93 | — | — | |
| 2-Methoxyethanol SCHEMBL1317307 | 0.93 | TSHR (0.47) | — | |
| 2-Methoxyethanol SCHEMBL28182844 | 0.90 | — | — | |
| 2-Methoxyethanol SCHEMBL4885313 | 0.90 | — | — | |
| 2-Methoxyethanol SCHEMBL2678565 | 0.90 | — | — | |
| 2-Methoxyethanol SCHEMBL3810075 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115025052-B | Calcium peroxide and manganese dioxide based nano particle with oxygen production and oxidation resistance and preparation method thereof | 天津大学 | 2023-04-18 | — | — | CN | claimed |
| CN-115025052-A | Calcium peroxide and manganese dioxide based nano particle with oxygen production and oxidation resistance and preparation method thereof | 天津大学 | 2022-09-09 | — | — | CN | claimed |
| CN-107245196-B | The preparation method of multilayer assembling micron size polystyrene magnetic composite microsphere | 成都爱兴生物科技有限公司 | 2019-07-09 | — | — | CN | claimed |
| CN-107245196-A | Multilayer assembles the preparation method of micron size polystyrene magnetic composite microsphere | 成都爱兴生物科技有限公司 | 2017-10-13 | — | — | CN | claimed |
| EP-2752900-B1 | PROCESS FOR PRODUCING HOLE BLOCKING LAYER, HOLE BLOCKING LAYER, PHOTOELECTRIC CONVERSION ELEMENT, PHOTOELECTRIC CONVERSION DEVICE, ORGANIC THIN-FILM SOLAR CELL PANEL, AND LIGHT-EMITTING DEVICE | IDEAL STAR INC (JP) | 2017-06-21 | — | — | EP | claimed |
| CN-104592506-A | N-methoxypolyethylene glycols-N,-carbamyl maleimide and preparation method thereof | UNIV SHENYANG TECHNOLOGY | 2015-05-06 | — | — | CN | claimed |
| EP-1577283-B1 | Removal of alcohols and water from a methylcyclopentadiene recycle stream in a process for the synthesis of methylcyclopentadienyl manganese tricarbonyl | AFTON CHEMICAL CORP (US) | 2008-11-12 | — | — | EP | claimed |
| CN-1970455-A | Manufacture method of lithium lanthanum titanium oxide | UNIV TSINGHUA (CN) | 2007-05-30 | — | — | CN | claimed |
| EP-0046819-B1 | REAGENT FOR THE QUANTITATIVE DETERMINATION OF WATER AND ITS USE THEREFOR | J.T. Baker Chemicals B.V. (NL) | 1985-01-23 | — | — | EP | claimed |
| EP-0023230-A1 | Reagent for the quantitative determination of water, and its use | J.T. Baker Chemicals B.V. (NL) | 1981-02-04 | — | — | EP | claimed |
| CN-117757353-A | Color-purifying heat-insulating coated glass and preparation method thereof | 昆明理工大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-112679430-B | Method for preparing isoquinolinones compound | 上海迪赛诺化学制药有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115025052-B | Calcium peroxide and manganese dioxide based nano particle with oxygen production and oxidation resistance and preparation method thereof | 天津大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-115025052-A | Calcium peroxide and manganese dioxide based nano particle with oxygen production and oxidation resistance and preparation method thereof | 天津大学 | 2022-09-09 | — | — | CN | disclosed |
| CN-111542572-B | Composition for marking of hard surface substrates | 可泰克斯公司 | 2022-04-29 | — | — | CN | disclosed |
| EP-0096214-A1 | Antibacterial pyrimidine compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-12-21 | — | — | EP | disclosed |
| US-4255471-A | AROMATIC BIS/ETHERDICARBOXYLIC ACID/ COMPOUNDS AND AN AROMATIC DIAMINE IN WATER AND AN APROTIC SOLVENT OR AN ALKYL ETHER OF ETHYLENE- OR DIETHYLENE-GLYCOL; STORAGE STABILITY | GENERAL ELECTRIC COMPANY (US) | 1981-03-10 | — | — | US | disclosed |
| EP-0023230-A1 | Reagent for the quantitative determination of water, and its use | J.T. Baker Chemicals B.V. (NL) | 1981-02-04 | — | — | EP | disclosed |
| US-4215157-A | Process for preparing polyetherimide coatings | GENERAL ELECTRIC COMPANY (US) | 1980-07-29 | — | — | US | disclosed |
| US-4157996-A | AROMATIC TETRACARBOXYLIC ACID CONTAINING TWO ETHER GROUPS, AROMATIC DIAMINE | GENERAL ELECTRIC COMPANY (US) | 1979-06-12 | — | — | US | disclosed |