SCHEMBL15225261

SCHEMBL15225261

CCCCCCCCCCCCCCCCc1ncccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.50
KCNH2 Q12809 2/20 0.48
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
GPR84 Q9NQS5 1/20 0.42
KDM4E B2RXH2 3/20 0.40
LMNA P02545 3/20 0.40
USP2 O75604 1/20 0.40
ALOX15 P16050 1/20 0.40
ALOX12 P18054 1/20 0.40
HTT P42858 1/20 0.40
NPC1 O15118 1/20 0.40
HSP90AA1 P07900 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
LIPG Q9Y5X9 1/20 0.39
ALDH1A1 P00352 1/20 0.39
ESR1 P03372 1/20 0.39
SHBG P04278 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27448272 1.00 NAAA (0.50) NAAAKCNH2TDP1L3MBTL1GPR84
SCHEMBL9009688 1.00 NAAA (0.50) NAAAKCNH2TDP1L3MBTL1GPR84
SCHEMBL7524061 1.00 NAAA (0.50) NAAAKCNH2TDP1L3MBTL1GPR84
SCHEMBL3233378 1.00 NAAA (0.50) NAAAKCNH2TDP1L3MBTL1GPR84
SCHEMBL9819021 1.00 NAAA (0.50) NAAAKCNH2TDP1L3MBTL1GPR84
SCHEMBL483412 1.00 NAAA (0.50) NAAAKCNH2TDP1L3MBTL1GPR84
SCHEMBL14305750 1.00 NAAA (0.50) NAAAKCNH2TDP1L3MBTL1GPR84
Bromide SCHEMBL27462623 0.98 NAAA (0.48) NAAAKCNH2TDP1L3MBTL1GPR84
Hydrochloric Acid SCHEMBL3003174 0.98 NAAA (0.48) NAAAKCNH2TDP1L3MBTL1GPR84
Methane SCHEMBL27634919 0.98 NAAA (0.48) NAAAKCNH2TDP1L3MBTL1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1888138-B1 IMPREGNATED POLYMER COMPOSITIONS AND DEVICES USING THEM ABIOMED INC (US) 2013-09-04 EP claimed
CN-101181227-B Solid lipid nanometer particle in-situ gel rubber preparations of biological adherent cyclosporine A and preparation method thereof UNIV SHENYANG PHARMACEUTICAL 2012-05-30 CN claimed
CN-101610798-A Drug releasing coatings for medical devices LUTONIX INC (US) 2009-12-23 CN claimed
CN-101181227-A Solid lipid nanometer particle in-situ gel rubber preparations of biological adherent cyclosporine A and preparation method thereof UNIV SHENYANG PHARMACEUTICAL (CN) 2008-05-21 CN claimed
CN-102046806-B Microarray system AKONNI BIOSYSTEMS (US) 2014-10-08 CN disclosed
CN-103547252-A Artificial oil bodies COMMW SCIENT IND RES ORG 2014-01-29 CN disclosed
CN-103271083-A Multi-functional ionic liquid compositions UNIV ALABAMA 2013-09-04 CN disclosed
CN-101610798-B Drug releasing coatings for medical devices LUTONIX INC 2013-07-17 CN disclosed
CN-101326275-B Multifunctional ionic liquid composition UNIV ALABAMA 2013-06-05 CN disclosed
CN-103040773-A Doxycycline metal complex in a solid dosage form GALEN CHEMICALS LTD 2013-04-17 CN disclosed
CN-101795707-B Compositions and methods for microbial storage and delivery CONJUGON INC 2013-03-27 CN disclosed
CN-101715349-B Therapeutic compositions and methods for treating gram-negative bacterial infections RQ BIOSCIENCE INC 2012-07-18 CN disclosed
CN-101010335-A Methods and compositions for treating gastrointestinal disorders MICROBIA INC (US) 2007-08-01 CN disclosed
CN-1893956-A Doxycycline metal complex solid dosage form GALEN CHEMICALS LTD (PR) 2007-01-10 CN disclosed
CN-1288445-C Method of counting keukocytes and leukocyte counter KOWA CO (JP) 2006-12-06 CN disclosed
CN-1849107-A Orally effective, essentially water-free topical agent containing one or several oxidation-sensitive substances DSM IP ASSETS BV (NL) 2006-10-18 CN disclosed
CN-1414865-A Treatment of cancer UNISEARCH LTD (AU) 2003-04-30 CN disclosed
CN-1082363-C Methods of using cyclicpolyanionic polyol derivatives for regulating skin wrinkles P & G CO (US) 2002-04-10 CN disclosed
CN-1285916-A Method of counting keukocytes and leukocyte counter KOWA CO (JP) 2001-02-28 CN disclosed
CN-1145584-A Methods of using cyclicpolyanionic polyol derivatives for regulating skin wrinkles PROCTER & GAMBLE (US) 1997-03-19 CN disclosed