Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 known ✓ | Q12809 | 2/20 | 0.47 |
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28291898 | 1.00 | NAAA (0.48) | NAAAKCNH2TDP1L3MBTL1GPR84 | |
| SCHEMBL27448272 | 0.98 | NAAA (0.50) | NAAAKCNH2TDP1L3MBTL1GPR84 | |
| SCHEMBL9009688 | 0.98 | NAAA (0.50) | NAAAKCNH2TDP1L3MBTL1GPR84 | |
| SCHEMBL3233378 | 0.98 | NAAA (0.50) | NAAAKCNH2TDP1L3MBTL1GPR84 | |
| SCHEMBL15225261 | 0.98 | NAAA (0.50) | NAAAKCNH2TDP1L3MBTL1GPR84 | |
| SCHEMBL7524061 | 0.98 | NAAA (0.50) | NAAAKCNH2TDP1L3MBTL1GPR84 | |
| SCHEMBL483412 | 0.98 | NAAA (0.50) | NAAAKCNH2TDP1L3MBTL1GPR84 | |
| SCHEMBL14305750 | 0.98 | NAAA (0.50) | NAAAKCNH2TDP1L3MBTL1GPR84 | |
| SCHEMBL9819021 | 0.98 | NAAA (0.50) | NAAAKCNH2TDP1L3MBTL1GPR84 | |
| Methane SCHEMBL27634919 | 0.95 | NAAA (0.48) | NAAAKCNH2TDP1L3MBTL1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888138-B1 | IMPREGNATED POLYMER COMPOSITIONS AND DEVICES USING THEM | ABIOMED INC (US) | 2013-09-04 | — | — | EP | claimed |
| JP-2008544769-A | — | — | 2008-12-11 | — | — | JP | claimed |
| EP-1888138-A2 | IMPREGNATED POLYMER COMPOSITIONS AND DEVICES USING THEM | Abiomed, Inc. (US) | 2008-02-20 | — | — | EP | claimed |
| WO-2006121908-A2 | IMPREGNATED POLYMER COMPOSITIONS AND DEVICES USING THEM | ABIOMED, INC. (US) | 2006-11-16 | — | — | WO | claimed |
| US-20060257355-A1 | Impregnated polymer compositions and devices using them | ABIOMED, INC. (US) | 2006-11-16 | — | — | US | claimed |
| CN-117838855-A | Synthetic adhesive limiting penetration of mucus | 北卡罗来纳大学查佩尔希尔分校 | 2024-04-09 | — | — | CN | disclosed |
| CN-116437810-A | Method for microbiome equilibration | 联合利华知识产权控股有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114585715-A | Home care products or formulations | 西姆莱斯有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-111133088-A | Active substance sheet | 西姆莱斯有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-108862527-A | Floatability green alga flocculating composition and the green alga minimizing technology for utilizing it | 顺天大学校产学协力团 | 2018-11-23 | — | — | CN | disclosed |
| EP-1888138-B1 | IMPREGNATED POLYMER COMPOSITIONS AND DEVICES USING THEM | ABIOMED INC (US) | 2013-09-04 | — | — | EP | disclosed |
| CN-101171265-B | Method of controlling the content of selected component(s) from polymer(s) using molecular sieve(s) | NOVOZYMES BIOPHARMA DK A/S (DK) | 2012-02-01 | — | — | CN | disclosed |
| EP-1879924-A2 | METHOD OF CONTROLLING THE CONTENT OF SELECTED COMPONENT(S) FROM POLYMER(S) USING MOLECULAR SIEVE(S) | Novozymes Biopolymer A/S (DK) | 2008-01-23 | — | — | EP | disclosed |
| US-20060287512-A1 | Method of controlling the content of selected component(s) from polymer(s) using molecular sieve(s) | NOVOZYMES BIOPOLYMER A/S (DK) | 2006-12-21 | — | — | US | disclosed |
| WO-2006121908-A2 | IMPREGNATED POLYMER COMPOSITIONS AND DEVICES USING THEM | ABIOMED, INC. (US) | 2006-11-16 | — | — | WO | disclosed |
| US-20060257355-A1 | Impregnated polymer compositions and devices using them | ABIOMED, INC. (US) | 2006-11-16 | — | — | US | disclosed |
| WO-2006117001-A2 | METHOD OF CONTROLLING THE CONTENT OF SELECTED COMPONENT(S) FROM POLYMER(S) USING MOLECULAR SIEVE(S) | NOVOZYMES BIOPOLYMER A/S (DK) | 2006-11-09 | — | — | WO | disclosed |
| CN-1406574-A | Cosmetic stick and prepared agents for skin containing amino substituted hydroxy diphenyl ketone | BASF AG (DE) | 2003-04-02 | — | — | CN | disclosed |
| CN-1406578-A | Cosmetic O/W emulsion and agents for skin containing amino sustituted hydroxy diphenyl ketone | BASF AG (DE) | 2003-04-02 | — | — | CN | disclosed |
| WO-1998030234-A1 | COMPOSITIONS FOR OSTEOGENESIS AND CHONDROGENESIS | IWAMOTO MASAHIRO (JP) | 1998-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060257355-A1 | Impregnated polymer compositions and devices using them | CD47, CD99, FGB | KCNH2 4243/4885HSP90AA1 912/4885NAAA 2073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.